{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T17:42:45Z","timestamp":1760982165579,"version":"3.40.4"},"reference-count":16,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2007,1,1]],"date-time":"2007-01-01T00:00:00Z","timestamp":1167609600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2007,1,1]],"date-time":"2007-01-01T00:00:00Z","timestamp":1167609600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur Neurol"],"published-print":{"date-parts":[[2007]]},"abstract":"<jats:p>Uremia-related restless legs syndrome (RLS) is a known form of secondary RLS. This cross-sectional survey included patients (n = 82) on stable hemodialysis (HD; &gt;3 months, Kt\/V &gt;1.2) who were iron-replete, free of neurodegenerative or psychiatric disorders, severe polyneuropathy and radiculopathy, not exposed to antipsychotics\/antidepressants, and not severely anemic. Forty-nine (60%) were RLS \u2018positive\u2019, and 25 (31%) had severe\/very severe symptoms (International Restless Legs Syndrome Study Group criteria). None had been diagnosed previously. In a multivariate analysis, the prevalence of RLS was higher in diabetic patients [vs. nondiabetics; prevalence ratio (PR) 2.32, 95% CI 1.50\u20133.60, p &lt; 0.001] and those exposed to Ca&lt;sup&gt;2+&lt;\/sup&gt; antagonists (vs. nonexposed; PR 2.02, CI 1.47\u20132.76, p &lt; 0.001), and also increased with dialysis duration (PR 1.05, 95% CI 1.02\u20131.09, p &lt; 0.001). Association of Ca&lt;sup&gt;2+&lt;\/sup&gt; antagonists and RLS in uremic patients has not been reported previously and deserves further research.<\/jats:p>","DOI":"10.1159\/000104718","type":"journal-article","created":{"date-parts":[[2007,7,4]],"date-time":"2007-07-04T14:10:31Z","timestamp":1183558231000},"page":"166-169","source":"Crossref","is-referenced-by-count":16,"title":["Restless Legs Syndrome in Hemodialysis Patients: Association with Calcium Antagonists"],"prefix":"10.1159","volume":"58","author":[{"given":"Sr\u0111ana","family":"Telarovi\u0107","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maja","family":"Relja","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vladimir","family":"Trkulja","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2007,6,29]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.pneurobio.2005.10.007"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1053%2Fj.ajkd.2004.01.007"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.smrv.2006.01.001"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1212%2F01.WNL.0000163996.64461.A3"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1053%2Fj.ajkd.2004.10.007"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.sleep.2004.01.014"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1093%2Fndt%2Fgfh654"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1053%2Fj.ajkd.2004.01.013"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016%2FS1389-9457%2802%2900073-4"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.0894-0959.2004.17329.x"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016%2FS1389-9457%2802%2900258-7"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1093%2Faje%2Fkwg074"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016%2FS0272-6386%2803%2900031-3"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1159%2F000087073"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1053%2Fajkd.1998.v31.pm9469505"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1469-7793.2000.t01-1-00461.x"}],"container-title":["European Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/104718","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/104718","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T02:57:47Z","timestamp":1745463467000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000104718"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007]]},"references-count":16,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2007,10,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000104718","archive":["Portico"],"relation":{},"ISSN":["0014-3022","1421-9913"],"issn-type":[{"type":"print","value":"0014-3022"},{"type":"electronic","value":"1421-9913"}],"subject":[],"published":{"date-parts":[[2007]]}}}