{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T18:44:40Z","timestamp":1757702680361,"version":"3.40.4"},"reference-count":9,"publisher":"S. Karger AG","issue":"2","license":[{"start":{"date-parts":[[2007,8,14]],"date-time":"2007-08-14T00:00:00Z","timestamp":1187049600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2007,8,14]],"date-time":"2007-08-14T00:00:00Z","timestamp":1187049600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiology"],"published-print":{"date-parts":[[2008]]},"abstract":"<i>Objectives:<\/i> To investigate outcome of pregnancy and fertility in women with double outlet right ventricle (DORV). <i>Methods:<\/i> Using 2 congenital heart disease registries, 21 female patients with DORV (aged 18\u201339 years) were retrospectively identified. Detailed recordings of each patient and their completed (>20 weeks gestation) pregnancies were recorded. <i>Results:<\/i> Overall, 10 patients had 19 pregnancies, including 3 spontaneous miscarriages (16%). During the 16 live birth pregnancies, primarily (serious) noncardiac complications were observed, e.g. premature labor\/delivery (n = 7 and n = 3, respectively), small for gestational age (n = 4), preeclampsia (n = 2) and recurrence of congenital heart disease (n = 2). Except for postpartum endocarditis and deterioration of subpulmonary obstruction, only mild cardiac complication pregnancies were recorded. Two women with children reported secondary female infertility. Several menstrual cycle disorders were reported: secondary amenorrhea (n = 4), primary amenorrhea (n = 3) and oligomenorrhea (n = 2). <i>Conclusion:<\/i> Successful pregnancy in women with DORV is possible. Primarily noncardiac complications were observed and only few (minor) cardiac complications. Infertility and menstrual cycle disorders appear to be more prevalent.<\/jats:p>","DOI":"10.1159\/000105550","type":"journal-article","created":{"date-parts":[[2007,8,15]],"date-time":"2007-08-15T14:58:41Z","timestamp":1187189921000},"page":"105-109","source":"Crossref","is-referenced-by-count":16,"title":["Fertility, Pregnancy and Delivery in Women after Biventricular Repair for Double Outlet Right Ventricle"],"prefix":"10.1159","volume":"109","author":[{"given":"Willem","family":"Drenthen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Petronella G.","family":"Pieper","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karin","family":"van der Tuuk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jolien W.","family":"Roos-Hesselink","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elke S.","family":"Hoendermis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adriaan A.","family":"Voors","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbara J.M.","family":"Mulder","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arie P.J.","family":"van Dijk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sing C.","family":"Yap","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hubert W.","family":"Vliegen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philip","family":"Moons","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tjark","family":"Ebels","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dirk J.","family":"van Veldhuisen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2007,8,14]]},"reference":[{"doi-asserted-by":"publisher","key":"ref1","DOI":"10.1016%2FS0003-4975%2801%2903079-X"},{"doi-asserted-by":"publisher","key":"ref2","DOI":"10.1111%2Fj.1479-828X.1998.tb03063.x"},{"doi-asserted-by":"publisher","key":"ref3","DOI":"10.1161%2Fhc3001.093437"},{"doi-asserted-by":"publisher","key":"ref4","DOI":"10.1007%2Fs00392-003-0880-0"},{"doi-asserted-by":"publisher","key":"ref5","DOI":"10.1016%2F0002-9149%2882%2990334-4"},{"doi-asserted-by":"publisher","key":"ref6","DOI":"10.1093%2Feurheartj%2Fehi472"},{"doi-asserted-by":"publisher","key":"ref7","DOI":"10.1093%2Feurheartj%2Fehi439"},{"doi-asserted-by":"publisher","key":"ref8","DOI":"10.1016%2FS0140-6736%2803%2914632-6"},{"doi-asserted-by":"publisher","key":"ref9","DOI":"10.1203%2F00006450-200003000-00006"}],"container-title":["Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/105550","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/105550","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T03:05:16Z","timestamp":1745463916000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000105550"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,8,14]]},"references-count":9,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2008,1,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000105550","archive":["Portico"],"relation":{},"ISSN":["0008-6312","1421-9751"],"issn-type":[{"type":"print","value":"0008-6312"},{"type":"electronic","value":"1421-9751"}],"subject":[],"published":{"date-parts":[[2007,8,14]]}}}