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Here we present the case of a generalized lichen nitidus with involvement of the palms in a patient with hepatitis C after systemic treatment with interferon \u03b1 and ribavirin. Furthermore in our patient we could show a strong lesional expression of MxA, a protein specifically induced by type I interferon. It is tempting to speculate that interferon \u03b1 may be involved in the pathogenesis of lichen nitidus.<\/jats:p>","DOI":"10.1159\/000106582","type":"journal-article","created":{"date-parts":[[2007,9,10]],"date-time":"2007-09-10T08:41:19Z","timestamp":1189413679000},"page":"236-239","source":"Crossref","is-referenced-by-count":17,"title":["Generalized Lichen Nitidus with Involvement of the Palms following Interferon \u03b1 Treatment"],"prefix":"10.1159","volume":"215","author":[{"given":"Marina","family":"Scheler","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julia","family":"Proelss","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wolfgang","family":"Br\u00e4uninger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Bieber","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joerg","family":"Wenzel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2007,9,12]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1007%2FBF01835934"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1001%2Farchderm.104.5.538"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1097%2F00000372-199904000-00009"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1440-0960.1989.tb00407.x"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1159%2F000076495"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-4362.1994.tb01074.x"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1525-1470.2005.22215.x"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016%2F0190-9622%2892%2970235-8"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1365-2133.2002.04700.x"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-4362.1986.tb02260.x"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-2133.1994.tb03421.x"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1159%2F000246351"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1097%2F00054725-200111000-00006"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-2133.1991.tb06078.x"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-4362.1988.tb01286.x"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1159%2F000086454"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1600-0714.2006.00402.x"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1600-0560.2006.00527.x"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-4632.2004.01933.x"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1468-3083.2003.00583.x"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1056%2FNEJM199811193392101"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1365-2133.2003.05481.x"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-2133.2005.06931.x"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1365-4362.2000.00868.x"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1472-8206.2000.tb00412.x"}],"container-title":["Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/106582","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/106582","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T02:39:43Z","timestamp":1745462383000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000106582"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007]]},"references-count":25,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2007,9,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000106582","archive":["Portico"],"relation":{},"ISSN":["1018-8665","1421-9832"],"issn-type":[{"type":"print","value":"1018-8665"},{"type":"electronic","value":"1421-9832"}],"subject":[],"published":{"date-parts":[[2007]]}}}