{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T11:34:46Z","timestamp":1790249686471,"version":"4.1.0"},"reference-count":20,"publisher":"S. Karger AG","issue":"2-3","license":[{"start":{"date-parts":[[2007,1,1]],"date-time":"2007-01-01T00:00:00Z","timestamp":1167609600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2007,1,1]],"date-time":"2007-01-01T00:00:00Z","timestamp":1167609600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Digestion"],"published-print":{"date-parts":[[2007]]},"abstract":"<jats:p>&lt;i&gt;Methods:&lt;\/i&gt; The efficacy of pancreatic stenting in the prevention of pancreatitis following endoscopic retrograde cholangiopancreatography (ERCP) was evaluated by a meta-analysis of 6 controlled studies; 12 additional uncontrolled studies were analyzed for rates of associated risk. &lt;i&gt;Results:&lt;\/i&gt; Post-ERCP pancreatitis (PEP) developed in 16.5% of controls, and in 5.1 or 9.6% of the stent group at the per-protocol (PP) or intention-to-treat (ITT) analyses. By analyzing only the 4 randomized trials, PEP developed in 24.1% of controls, and in 6.1 or 12.0% of the stented patients at the PP or ITT analyses. Risk was significantly lower in the stent group when compared with controls: OR 0.44 (95% CI 0.24\u20130.81). The absolute risk reduction is 12.0 (95% CI 3.0\u201321.0), the number needed to treat 8 (95% CI 5\u201334), and the publication bias 2. ORs for mild to moderate PEP were reduced in the stent group (OR = 0.537, 95% CI 0.283\u20131.021), as were those for severe PEP (OR = 0.123, 95% CI 0.021\u20130.726). Non-pancreatic complications were 4.2%, and included early stent migration (1.4%), perforations (0.4%), bleeding (1.4%), and infections (1.0%). &lt;i&gt;Conclusion:&lt;\/i&gt; Available trials show benefit for pancreatic stenting in the prophylaxis of PEP, but more randomized studies are needed before endorsing a routine use of this endoscopic procedure.<\/jats:p>","DOI":"10.1159\/000106774","type":"journal-article","created":{"date-parts":[[2007,8,8]],"date-time":"2007-08-08T15:14:40Z","timestamp":1186586080000},"page":"156-163","source":"Crossref","is-referenced-by-count":68,"title":["Pancreatic Duct Stents in the Prophylaxis of Pancreatic Damage after Endoscopic Retrograde Cholangiopancreatography: A Systematic Analysis of Benefits and Associated Risks"],"prefix":"10.1159","volume":"75","author":[{"given":"Angelo","family":"Andriulli","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosario","family":"Forlano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grazia","family":"Napolitano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pasquale","family":"Conoscitore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nazario","family":"Caruso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Pilotto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pier Luigi","family":"Di Sebastiano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gioacchino","family":"Leandro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2007,8,6]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.gie.2006.10.030"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016%2FS0016-5107%2804%2902013-9"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.gie.2006.01.058"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1067%2Fmge.2003.124"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016%2FS0016-5107%2893%2970217-5"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016%2FS0016-5085%2898%2970031-9"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.gie.2005.04.020"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1055%2Fs-2007-1010649"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016%2FS0016-5107%2895%2970051-X"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016%2FS0016-5107%2895%2970127-3"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016%2FS0016-5107%2896%2980456-1"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016%2FS0016-5107%2896%2980488-3"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016%2FS0016-5107%2898%2970320-7"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1055%2Fs-2002-23629"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016%2FS0016-5107%2802%2970184-3"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016%2FS0016-5107%2803%2902366-6"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016%2FS1542-3565%2804%2900062-X"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016%2F0197-2456%2895%2900134-4"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1177%2F0272989X9501500112"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1002%2F1097-0142%2819860915%2958%3A6%3C1378%3A%3AAID-CNCR2820580635%3E3.0.CO%3B2-S"}],"container-title":["Digestion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/106774","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/106774","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T02:42:05Z","timestamp":1745462525000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000106774"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007]]},"references-count":20,"journal-issue":{"issue":"2-3","published-online":{"date-parts":[[2007,8,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000106774","archive":["Portico"],"relation":{},"ISSN":["0012-2823","1421-9867"],"issn-type":[{"value":"0012-2823","type":"print"},{"value":"1421-9867","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007]]}}}