{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,11]],"date-time":"2026-04-11T01:00:06Z","timestamp":1775869206307,"version":"3.50.1"},"reference-count":8,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2007,1,1]],"date-time":"2007-01-01T00:00:00Z","timestamp":1167609600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2007,1,1]],"date-time":"2007-01-01T00:00:00Z","timestamp":1167609600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur Neurol"],"published-print":{"date-parts":[[2007]]},"abstract":"<jats:p>&lt;i&gt;Background:&lt;\/i&gt; Only a few non-recent studies assessed the importance of hematocrit (HCT) in patients with ischemic stroke. We evaluated how HCT might affect early mortality after stroke. &lt;i&gt;Methods:&lt;\/i&gt; We investigated all first-ever ischemic strokes included in the population-based L\u2019Aquila registry. 3,481 patients according to HCT (%) values were included into four categories (\u226440, 41\u201345, 46\u201350, and &gt;50). &lt;i&gt;Results: &lt;\/i&gt;There were more men than women with HCT &gt;50 (6.6 vs. 2.8%; p &lt; 0.0001) and more women than men with HCT \u226440 (48.5 vs. 37.9%; p &lt; 0.0001). Proportions of chronic atrial fibrillation (p = 0.0053) increased in women from the lower to the higher HCT categories. 7- and 28-day case-fatality rates were similar in men and women in the lower HCT categories but higher in women than in men in the higher categories. At the 28-day Kaplan-Meier analysis, men had similar survivals in the different categories while women with HCT &gt;50 showed the worst survival (p &lt; 0.0001). At the multivariate Cox regression analysis HCT 46\u201350 and &gt;50 was an independent predictor of mortality in women within 28 days. &lt;i&gt;Conclusion:&lt;\/i&gt;High HCT might represent in women a previously underestimated independent predictor of mortality after ischemic stroke. Consideration of HCT in future stroke trials would be useful for ameliorating stroke care, especially in women.<\/jats:p>","DOI":"10.1159\/000107946","type":"journal-article","created":{"date-parts":[[2007,9,10]],"date-time":"2007-09-10T08:41:19Z","timestamp":1189413679000},"page":"233-238","source":"Crossref","is-referenced-by-count":30,"title":["Contribution of Hematocrit to Early Mortality after Ischemic Stroke"],"prefix":"10.1159","volume":"58","author":[{"given":"Simona","family":"Sacco","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carmine","family":"Marini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luigi","family":"Olivieri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesca","family":"Pistoia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Carolei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2007,9,7]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016%2F0002-8703%2894%2990679-3"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-2796.1994.tb01050.x"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016%2FS0003-9993%2803%2900009-1"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1093%2Fbrain%2F99.2.193"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016%2FS1474-4422%2803%2900266-7"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016%2F0140-6736%2891%2993206-O"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1212%2F01.wnl.0000183057.96792.a8"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016%2F0021-9150%2892%2990234-8"}],"container-title":["European Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/107946","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/107946","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T02:54:22Z","timestamp":1745463262000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000107946"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007]]},"references-count":8,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2007,11,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000107946","archive":["Portico"],"relation":{},"ISSN":["0014-3022","1421-9913"],"issn-type":[{"value":"0014-3022","type":"print"},{"value":"1421-9913","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007]]}}}