{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T04:56:41Z","timestamp":1745470601632,"version":"3.40.4"},"reference-count":46,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2007,11,19]],"date-time":"2007-11-19T00:00:00Z","timestamp":1195430400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2007,11,19]],"date-time":"2007-11-19T00:00:00Z","timestamp":1195430400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dement Geriatr Cogn Disord"],"published-print":{"date-parts":[[2008]]},"abstract":"<jats:p>&lt;i&gt;Background\/Aims:&lt;\/i&gt; The impact of vitamin B status on cognitive functioning in Alzheimer\u2019s disease (AD) is disputed. Using a population-based sample, we examined the associations of vitamin B&lt;sub&gt;12&lt;\/sub&gt; and folate with cognitive functioning in clinical (n = 44) and preclinical (n = 39) AD. &lt;i&gt;Methods:&lt;\/i&gt; The groups were subdivided in terms of low (&lt;200 pmol\/l) versus normal levels of B&lt;sub&gt;12&lt;\/sub&gt; and low (&lt;13 nmol\/l) versus normal folate levels. Participants were administered tests of verbal and nonverbal episodic memory, visuospatial abilities and verbal fluency. &lt;i&gt;Results:&lt;\/i&gt; As expected, the preclinical AD group performed better than the AD group across most cognitive tests. More interestingly, the effects of low vitamin B&lt;sub&gt;12&lt;\/sub&gt; and folate levels were negligible across all cognitive tests in clinical and preclinical AD. &lt;i&gt;Conclusion:&lt;\/i&gt; These findings suggest that the influence of vitamin B deficiency on cognitive functioning is overshadowed by the neurodegenerative processes associated with AD.<\/jats:p>","DOI":"10.1159\/000111129","type":"journal-article","created":{"date-parts":[[2007,11,23]],"date-time":"2007-11-23T11:08:56Z","timestamp":1195816136000},"page":"23-31","source":"Crossref","is-referenced-by-count":4,"title":["Vitamin B Status and Cognitive Performance in Preclinical and Clinical Alzheimer\u2019s Disease: Data from the Kungsholmen 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