{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T12:18:36Z","timestamp":1779106716789,"version":"3.51.4"},"reference-count":22,"publisher":"S. Karger AG","issue":"3-4","license":[{"start":{"date-parts":[[2007,1,1]],"date-time":"2007-01-01T00:00:00Z","timestamp":1167609600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2007,1,1]],"date-time":"2007-01-01T00:00:00Z","timestamp":1167609600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuroepidemiology"],"published-print":{"date-parts":[[2007]]},"abstract":"<i>Background\/Aims:<\/i> Gait speed is cross-sectionally associated with attention and psychomotor speed in older community dwellers. It is unclear if gait speed predicts decline in these cognitive domains over time. <i>Methods:<\/i> Usual gait speed (m\/s) over 6 m was measured at baseline in 2,776 Health, Aging and Body Composition Study participants (mean age \u00b1 SD 73.5 \u00b1 2.8 years, 53% women, 37% blacks). The Digit Symbol Substitution Test (DSST) was administered at baseline and after 5 years to assess attention and psychomotor speed. We used multivariate logistic regression models to calculate the risk of DSST 5-year decline [>1 SD from mean change (9 points)] across quartiles of gait speed, adjusting for demographics, weight, physical activity, comorbidities, depression and Modified Mini-Mental State Examination. <i>Results:<\/i> After 5 years, 389 (17.1%) participants declined in DSST. Compared to those in the highest quartile of gait speed (>1.35 m\/s), participants in the lowest quartile (<1.05 m\/s) were more likely to decline in DSST independently of the considered covariates (OR 1.74, 95% CI 1.21\u20132.51, adjusted p for trend across quartiles = 0.006). <i>Conclusions:<\/i> In this cohort of older community dwellers, gait speed independently predicted a decline in DSST after 5 years.<\/jats:p>","DOI":"10.1159\/000111577","type":"journal-article","created":{"date-parts":[[2007,11,27]],"date-time":"2007-11-27T15:20:12Z","timestamp":1196176812000},"page":"156-162","source":"Crossref","is-referenced-by-count":162,"title":["Gait Speed Predicts Decline in Attention and Psychomotor Speed in Older Adults: The Health Aging and Body Composition Study"],"prefix":"10.1159","volume":"29","author":[{"given":"Marco","family":"Inzitari","sequence":"first","affiliation":[]},{"given":"Anne B.","family":"Newman","sequence":"additional","affiliation":[]},{"given":"Kristine","family":"Yaffe","sequence":"additional","affiliation":[]},{"given":"Robert","family":"Boudreau","sequence":"additional","affiliation":[]},{"given":"Nathalie","family":"de Rekeneire","sequence":"additional","affiliation":[]},{"given":"Ronald","family":"Shorr","sequence":"additional","affiliation":[]},{"given":"Tamara B.","family":"Harris","sequence":"additional","affiliation":[]},{"given":"Caterina","family":"Rosano","sequence":"additional","affiliation":[]}],"member":"127","published-online":{"date-parts":[[2007,11,27]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1159%2F000081043"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1056%2FNEJMoa020441"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1212%2F01.WNL.0000162054.15428.E9"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1001%2Farchinte.166.10.1115"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1001%2Farchneur.59.4.601"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1212%2F01.WNL.0000161850.01792.77"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1176%2Fappi.ajgp.13.2.134"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1001%2Fjama.279.8.585"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1093%2Faje%2Fkwf209"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1161%2F01.STR.0000149625.99732.69"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1159%2F000096792"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1093%2Fgerona%2F55.4.M221"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1532-5415.2003.51104.x"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1097%2F00005768-200009001-00009"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1001%2Farchinte.161.14.1703"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1136%2Fjnnp.2003.026260"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1532-5415.2005.53368.x"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1001%2Farchinte.163.19.2315"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1080%2F01688639708403741"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1159%2F000067110"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1136%2Fjnnp.2006.106914"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1093%2Faje%2Fkwk017"}],"container-title":["Neuroepidemiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/111577","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/111577","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T02:18:06Z","timestamp":1745461086000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000111577"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007]]},"references-count":22,"journal-issue":{"issue":"3-4","published-online":{"date-parts":[[2008,2,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000111577","archive":["Portico"],"relation":{},"ISSN":["0251-5350","1423-0208"],"issn-type":[{"value":"0251-5350","type":"print"},{"value":"1423-0208","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007]]}}}