{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T04:57:34Z","timestamp":1745470654296,"version":"3.40.4"},"reference-count":17,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2008,1,1]],"date-time":"2008-01-01T00:00:00Z","timestamp":1199145600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2008,1,1]],"date-time":"2008-01-01T00:00:00Z","timestamp":1199145600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Haematol"],"published-print":{"date-parts":[[2008]]},"abstract":"<jats:p>&lt;i&gt;Background:&lt;\/i&gt; Acquired factor VIII inhibitor is an antibody formed against FVIII and seen in patients without FVIII replacement therapy. This entity has been associated with both autoimmune disease and infections. &lt;i&gt;Case Study:&lt;\/i&gt; We report the case of a 65-year-old man with dermatomyositis who presented with a bleeding episode following venipuncture and hematuria. His coagulation parameters were followed as well as the inhibitor level. His acquired FVIII inhibitor was managed successfully with rituximab. &lt;i&gt;Conclusion:&lt;\/i&gt; Our patient\u2019s bleeding episodes resolved and the inhibitor level was undetectable after 12 months. This is the first case of acquired FVIII inhibitor in association with dermatomyositis.<\/jats:p>","DOI":"10.1159\/000112838","type":"journal-article","created":{"date-parts":[[2008,1,4]],"date-time":"2008-01-04T13:12:59Z","timestamp":1199452379000},"page":"8-11","source":"Crossref","is-referenced-by-count":3,"title":["Acquired Factor VIII Inhibitor in a Patient with Dermatomyositis \u2013 A Case Study"],"prefix":"10.1159","volume":"119","author":[{"given":"Ayodele","family":"Ayoola","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wajahath","family":"Mohsini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sein","family":"Aung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2008,1,4]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1365-2141.2003.04162.x"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1365-2516.2003.00857.x"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1002%2Fart.1780400426"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-2141.1985.tb02972.x"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016%2FS0950-3536%2896%2980067-9"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1073%2Fpnas.89.9.3795"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1007%2Fs002770050263"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1538-7836.2007.02433.x"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-2141.1981.00635.x"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1365-2516.2001.00489.x"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1182%2Fblood.V98.4.952"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1182%2Fblood-2002-09-2856"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-2516.2005.01136.x"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1182%2Fblood-2002-03-0765"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1365-2141.2002.03835_5.x"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-2516.2005.01060.x"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1080%2F10428190701411441"}],"container-title":["Acta Haematologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/112838","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/112838","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T02:32:40Z","timestamp":1745461960000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000112838"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008]]},"references-count":17,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2008,3,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000112838","archive":["Portico"],"relation":{},"ISSN":["0001-5792","1421-9662"],"issn-type":[{"type":"print","value":"0001-5792"},{"type":"electronic","value":"1421-9662"}],"subject":[],"published":{"date-parts":[[2008]]}}}