{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T16:51:49Z","timestamp":1758819109355,"version":"3.40.4"},"reference-count":17,"publisher":"S. Karger AG","issue":"2","license":[{"start":{"date-parts":[[2008,1,1]],"date-time":"2008-01-01T00:00:00Z","timestamp":1199145600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2008,1,1]],"date-time":"2008-01-01T00:00:00Z","timestamp":1199145600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Skin Pharmacol Physiol"],"published-print":{"date-parts":[[2008]]},"abstract":"<jats:p>The aim of this study was to investigate the prevention of the dermal colonization of methicillin-resistant&lt;i&gt; Staphylococcus aureus &lt;\/i&gt;(MRSA) strains by the application of micro- and nanoparticles called Maresome\u2122. Maresome\u2122 were prepared from selected microalgae by a novel emulsion technique. They contain lipids and all other components of the microalgae in an encapsulated form. It could be shown that Maresome\u2122 prepared from a cyanobacterial strain of the order Nostocales (Bio33-Maresome\u2122) were able to inhibit the dermal colonization of different MRSA strains (North German Epidemic Strain, Col, N315) and even of the vancomycin-resistant strain MU50 in the models \u2018mouse ear\u2019 and \u2018cow udder teat\u2019. Pretreatment of the skin with Maresome\u2122 reduced the number of attached MRSA by 3\u20134 log units in comparison to the control. We assume that a prophylactic skin care with Maresome\u2122 could complete the multibarrier anti-infectious strategy against MRSA.<\/jats:p>","DOI":"10.1159\/000113066","type":"journal-article","created":{"date-parts":[[2008,1,14]],"date-time":"2008-01-14T14:38:34Z","timestamp":1200321514000},"page":"98-105","source":"Crossref","is-referenced-by-count":10,"title":["Inhibition of Dermal MRSA Colonization by Microalgal Micro- and Nanoparticles"],"prefix":"10.1159","volume":"21","author":[{"given":"G.","family":"Lukowski","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"U.","family":"Lindequist","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Mundt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Kramer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.-D.","family":"J\u00fclich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2008,1,14]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1469-0691.2006.01343.x"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.2217%2F1745509X.2.1.37"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1186%2F1476-0711-3-9"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1007%2FBF00446929"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1128%2FAAC.00521-06"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016%2FS0002-9343%2898%2900149-1"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1128%2FJB.187.7.2426-2438.2005"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1078%2F1438-4639-00045"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016%2FS0378-5173%2898%2900091-X"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1159%2F000098701"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1128%2FIAI.69.5.3423-3426.2001"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1126%2Fscience.186.4158.19"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1007%2Fs11745-006-5048-z"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1159%2F000069757"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1574-6968.2007.00772.x"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1038%2Fnm0504-447a"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.chom.2007.04.005"}],"container-title":["Skin Pharmacology and Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/113066","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/113066","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T02:35:33Z","timestamp":1745462133000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000113066"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008]]},"references-count":17,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2008,3,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000113066","archive":["Portico"],"relation":{},"ISSN":["1660-5527","1660-5535"],"issn-type":[{"type":"print","value":"1660-5527"},{"type":"electronic","value":"1660-5535"}],"subject":[],"published":{"date-parts":[[2008]]}}}