{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T02:45:14Z","timestamp":1790649914629,"version":"4.1.0"},"reference-count":30,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2008,1,1]],"date-time":"2008-01-01T00:00:00Z","timestamp":1199145600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2008,1,1]],"date-time":"2008-01-01T00:00:00Z","timestamp":1199145600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dement Geriatr Cogn Disord"],"published-print":{"date-parts":[[2008]]},"abstract":"<i>Aim:<\/i> To investigate the relationship between performance in language tests and levels of brain metabolites in two selected left temporal lobe regions. <i>Methods:<\/i> Ninety-five subjects were included: 26 controls, 30 amnestic mild cognitive impairment subjects, 27 Alzheimer\u2019s disease and 12 frontotemporal lobar degeneration (FTLD) patients. Language was assessed by a naming test: Boston Naming Test (BNT) and by a semantic verbal fluency test. Other cognitive functions: verbal and visual memory, visual perception, attention and executive function, and praxis were also assessed. Single voxel magnetic resonance spectroscopy was obtained in the left temporal pole (L-TPOLE), and in the left posterior temporoparietal region (L-TPAR). <i>Results:<\/i> BNT scores were significantly associated with N-acetylaspartate\/creatine ratios (r = 0.45; p < 0.001) and choline\/creatine ratios (r = 0.33; p < 0.005) in the L-TPOLE. No significant associations were found between BNT and metabolite levels in the L-TPAR. No significant associations were found between the semantic verbal fluency test and other cognitive tests and metabolite levels either in the L-TPOLE or in the L-TPAR. <i>Conclusion:<\/i> Naming performance is related to metabolite levels in the anterior L-TPOLE.<\/jats:p>","DOI":"10.1159\/000113728","type":"journal-article","created":{"date-parts":[[2008,1,28]],"date-time":"2008-01-28T07:48:52Z","timestamp":1201506532000},"page":"212-217","source":"Crossref","is-referenced-by-count":12,"title":["Naming Is Associated with Left Temporal Pole Metabolite Levels in Neurodegenerative 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