{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T11:41:16Z","timestamp":1774266076941,"version":"3.50.1"},"reference-count":13,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2008,1,1]],"date-time":"2008-01-01T00:00:00Z","timestamp":1199145600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2008,1,1]],"date-time":"2008-01-01T00:00:00Z","timestamp":1199145600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Public Health Genomics"],"published-print":{"date-parts":[[2008]]},"abstract":"<jats:p>&lt;i&gt;Objectives:&lt;\/i&gt; In this paper we describe the outline and results of a 7-year screening programme for thalassaemias and glucose-6-phosphate dehydrogenase (G6PD) deficiency in 13- to 14-year-old students from the Sardinian population. &lt;i&gt;Method:&lt;\/i&gt; This programme had several steps: formal education on thalassaemia, request of informed consent by parents, blood testing and genetic counselling. &lt;i&gt;Results:&lt;\/i&gt;Out of 63,285 subjects tested, 6,521 (10.3%) were heterozygotes for \u03b2-thalassaemia, 16,175 (25.6%) for \u03b1-thalassaemia and 101 were carriers of a haemoglobin variant. One thousand four hundred and twenty (16.4%) males were hemizygotes for G6PD deficiency and 1,893 (20.6%) females were heterozygotes. &lt;i&gt;Conclusion:&lt;\/i&gt; The uptake of the programme was remarkably high and homogeneous across the island, indicating and confirming a great interest of the Sardinian population in any initiative directed at the prevention of homozygous \u03b2-thalassaemia.<\/jats:p>","DOI":"10.1159\/000113873","type":"journal-article","created":{"date-parts":[[2008,3,28]],"date-time":"2008-03-28T20:47:51Z","timestamp":1206737271000},"page":"121-128","source":"Crossref","is-referenced-by-count":14,"title":["Thalassaemia and Glucose-6-Phosphate Dehydrogenase Screening in 13- to 14-Year-Old Students of the Sardinian Population: Preliminary Findings"],"prefix":"10.1159","volume":"11","author":[{"given":"A.","family":"Cao","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Congiu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.C.","family":"Sollaino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.F.","family":"Desogus","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.R.","family":"Demartis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Loi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Cau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Galanello","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2008,3,26]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016%2FS0950-3536%2805%2980072-1"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016%2FS0889-8545%2801%2900006-7"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016%2FS0140-6736%2881%2991682-2"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1002%2Fajmg.1320060304"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1155%2FS1463924695000125"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1001%2Fjama.278.15.1273"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1002%2Fajh.2830460204"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1002%2F%28SICI%291096-8652%28199812%2959%3A4%3C273%3A%3AAID-AJH2%3E3.0.CO%3B2-3"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1038%2Fsj.ejhg.5201113"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1056%2FNEJM199705013361810"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.3109\/15412555.2010.510160"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1378\/chest.06-2336"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1378\/chest.08-0047"}],"container-title":["Public Health Genomics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/113873","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/113873","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T01:53:40Z","timestamp":1745459620000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000113873"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008]]},"references-count":13,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2008,3,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000113873","archive":["Portico"],"relation":{},"ISSN":["1662-4246","1662-8063"],"issn-type":[{"value":"1662-4246","type":"print"},{"value":"1662-8063","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008]]}}}