{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T17:47:24Z","timestamp":1760982444582,"version":"3.40.4"},"reference-count":19,"publisher":"S. Karger AG","issue":"3-4","license":[{"start":{"date-parts":[[2008,1,1]],"date-time":"2008-01-01T00:00:00Z","timestamp":1199145600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2008,1,1]],"date-time":"2008-01-01T00:00:00Z","timestamp":1199145600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur Neurol"],"published-print":{"date-parts":[[2008]]},"abstract":"<jats:p>The auditory startle response (ASR) is a brainstem reflex elicited by an unexpected acoustic stimulus. In focal dystonia (FD), the excitability of brainstem neurons is abnormally enhanced. To identify a possible impact of this pathology on the processing of acoustic stimuli, we studied the habituation of the ASR in patients (n = 11) with FD and compared the findings to those of patients with Parkinson\u2019s disease (PD; n = 11) and controls (n = 11). Latencies in FD patients did not differ from those of controls but were delayed in PD patients compared to controls (p &lt; 0.0001). Habituation was normal at the orbicularis oculi muscles but reduced at the sternocleidomastoid muscles in FD (p = 0.005). Habituation in PD was comparable to controls. Normal latencies and sequence activation indicate intact neural pathways mediating the ASR in FD. Impaired habituation of the ASR points towards a reduced inhibition of acoustic stimuli in FD.<\/jats:p>","DOI":"10.1159\/000114038","type":"journal-article","created":{"date-parts":[[2008,1,30]],"date-time":"2008-01-30T11:02:04Z","timestamp":1201690924000},"page":"172-178","source":"Crossref","is-referenced-by-count":6,"title":["Habituation of the Auditory Startle Response in Cervical Dystonia and Parkinson\u2019s Disease"],"prefix":"10.1159","volume":"59","author":[{"given":"Norman","family":"Putzki","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karoline","family":"Graf","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philipp","family":"Stude","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans-Christoph","family":"Diener","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthias","family":"Maschke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2008,1,29]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1002%2Fmds.10327"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1093%2Fbrain%2F123.1.42"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1002%2Fmds.870030108"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1097%2F00002826-199406000-00002"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016%2FS0301-0082%2898%2900098-7"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016%2F0006-8993%2890%2991754-5"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1093%2Fbrain%2F114.4.1891"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1093%2Fbrain%2F115.4.1181"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016%2F0168-5597%2892%2990111-N"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1002%2Fmds.10609"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1159%2F000137111"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1007%2Fs002210000417"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1469-8986.1989.tb03149.x"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1002%2F1531-8257%28200101%2916%3A1%3C62%3A%3AAID-MDS1002%3E3.0.CO%3B2-V"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016%2FS0301-0082%2897%2900031-2"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1006%2Fnlme.1996.0044"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1002%2Fmds.10063"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1136%2Fjnnp.65.5.771"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016%2FS0006-8993%2897%2900027-9"}],"container-title":["European Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/114038","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/114038","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T01:55:25Z","timestamp":1745459725000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000114038"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008]]},"references-count":19,"journal-issue":{"issue":"3-4","published-online":{"date-parts":[[2008,2,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000114038","archive":["Portico"],"relation":{},"ISSN":["0014-3022","1421-9913"],"issn-type":[{"type":"print","value":"0014-3022"},{"type":"electronic","value":"1421-9913"}],"subject":[],"published":{"date-parts":[[2008]]}}}