{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T04:11:18Z","timestamp":1777867878265,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2008,1,31]],"date-time":"2008-01-31T00:00:00Z","timestamp":1201737600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2008,1,31]],"date-time":"2008-01-31T00:00:00Z","timestamp":1201737600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur Neurol"],"abstract":"<jats:p>21 patients with intracranial obstruction of an internal carotid artery (ICA) (15 stenoses, 6 occlusions) were studied for angiographic, clinical and prognostic evaluation. Evidence of atheromatous changes and associated risk factors did not significantly differ from age- and sex-matched controls with extracranial ICA disease. No significant difference occurred between matched groups with extra- or intracranial ICA obstruction in functional outcome, delayed strokes, TIAs and death, suggesting that prognosis was more related to age, sex and degree of obstruction than to level of obstruction. 80% intracranial stenosis patients had the worst functional outcome, 30\u201360% stenosis patients the best, and occlusion patients were intermediate. This corresponded to higher risk of delayed stroke in patients with 80% stenosis. The prognosis was better in patients without evidence of proximal atheromatosis. Only 1 patient with intracranial occlusion suffered delayed homolateral TIAs in which atheromatous embolization from stenosed contralateral ICA was hypothetized.<\/jats:p>","DOI":"10.1159\/000115582","type":"journal-article","created":{"date-parts":[[2008,2,1]],"date-time":"2008-02-01T05:26:52Z","timestamp":1201843612000},"page":"351-358","source":"Crossref","is-referenced-by-count":17,"title":["Prognosis of Symptomatic Intracranial Obstruction of Internal Carotid Artery"],"prefix":"10.1159","author":[{"given":"J.","family":"Bogousslavsky","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Regli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2008,1,31]]},"container-title":["European Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/115582","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000115582","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T11:07:14Z","timestamp":1777547234000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000115582"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,1,31]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000115582","archive":["Portico"],"relation":{},"ISSN":["0014-3022","1421-9913"],"issn-type":[{"value":"0014-3022","type":"print"},{"value":"1421-9913","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,1,31]]}}}