{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T08:19:03Z","timestamp":1789201143576,"version":"build-2803163510"},"reference-count":33,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2008,1,1]],"date-time":"2008-01-01T00:00:00Z","timestamp":1199145600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2008,1,1]],"date-time":"2008-01-01T00:00:00Z","timestamp":1199145600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Psychother Psychosom"],"published-print":{"date-parts":[[2008]]},"abstract":"<jats:p>&lt;i&gt;Background:&lt;\/i&gt; Attention models view attention as having at least two components: endogenous attention defined as executive and directed by voluntary acts, and exogenous attention defined as automatic and directed by external stimulation. &lt;i&gt;Methods:&lt;\/i&gt; Three studies (2 of our own) were designed to evaluate the decline of these two components of attention in normal aging and two neurodegenerative diseases. Standardized tests derived from Posner\u2019s model of visuospatial attention were administered to normal healthy elderly participants (n = 13), patients suffering from Huntington\u2019s disease (HD; n = 17) and Alzheimer\u2019s disease (n = 15), and matched control subjects (n = 57). Outcome measures were reaction time (RT) and RT difference score (defined as invalid RT minus valid RT). &lt;i&gt;Results:&lt;\/i&gt; In healthy elderly participants, the decline was more pronounced for endogenous attention in situations of perceptual conflict. In Alzheimer\u2019s disease, there was a significant decline in both attention components, while in HD, voluntary attention was markedly impaired and automatic attention preserved. &lt;i&gt;Conclusions:&lt;\/i&gt; Normal aging and HD are characterized by decreased endogenous attention in situations of perceptual conflict. Our data support previous findings that older people display impairment of attention in complex perceptual situations. We propose a model which allows for the separation of attention pathologies, thus improving therapeutic strategies for patients and elderly.<\/jats:p>","DOI":"10.1159\/000116607","type":"journal-article","created":{"date-parts":[[2008,2,15]],"date-time":"2008-02-15T15:20:14Z","timestamp":1203088814000},"page":"139-146","source":"Crossref","is-referenced-by-count":5,"title":["Normal and Pathological Aging of Attention in Presymptomatic Huntington\u2019s, Huntington\u2019s and Alzheimer\u2019s Disease, and Nondemented Elderly 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