{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T04:12:53Z","timestamp":1777867973555,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2008,2,12]],"date-time":"2008-02-12T00:00:00Z","timestamp":1202774400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2008,2,12]],"date-time":"2008-02-12T00:00:00Z","timestamp":1202774400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur Neurol"],"abstract":"<jats:p>The relationship between anatomical configuration of collateral flow and the outcome of the internal carotid artery (ICA) occlusion was analyzed. Sixty-one patients with occlusion of ICA were studied with transcranial Doppler ultrasonography. The authors monitored blood flow velocities in the middle cerebral artery (MCA) ipsilateral to the ICA occlusion during a series of carotid compressions. Blood flow through three major collateral arteries (anterior and posterior communicating arteries and ophthalmic artery) was determined as a residual flow in MCA after each compression. Twelve subjects had asymptomatic occlusion and 46 had stroke; patients with stroke were divided into mild, moderate, and severe stroke groups. Subjects with asymptomatic occlusion had a higher number of patent collateral vessels than severe stroke patients (p &lt; 0.001). The same relationship was found between mild and severe stroke patients (p &lt; 0.001) and between moderate and severe stroke (p &lt; 0.01). Patients with watershed ischemia had a lower number of patent collateral arteries than patients with thromboembolic ischemia as revealed by CT examination (p &lt; 0.02). This study demonstrates the crucial role of collateral flow in the stroke pathogenesis and stroke outcome in subjects with extracranial ICA occlusions.<\/jats:p>","DOI":"10.1159\/000117130","type":"journal-article","created":{"date-parts":[[2008,2,13]],"date-time":"2008-02-13T06:19:14Z","timestamp":1202883554000},"page":"212-216","source":"Crossref","is-referenced-by-count":26,"title":["Effect of Collateral Flow Patterns on Outcome of Carotid Occlusion"],"prefix":"10.1159","author":[{"given":"Peter","family":"Hedera","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jarmila","family":"Bujd\u00e1kov\u00e1","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pavel","family":"Traubner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2008,2,12]]},"container-title":["European Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/117130","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000117130","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T11:16:31Z","timestamp":1777547791000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000117130"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,2,12]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000117130","archive":["Portico"],"relation":{},"ISSN":["0014-3022","1421-9913"],"issn-type":[{"value":"0014-3022","type":"print"},{"value":"1421-9913","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,2,12]]}}}