{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T23:06:18Z","timestamp":1782601578664,"version":"3.54.5"},"reference-count":14,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2008,3,13]],"date-time":"2008-03-13T00:00:00Z","timestamp":1205366400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"},{"start":{"date-parts":[[2008,3,13]],"date-time":"2008-03-13T00:00:00Z","timestamp":1205366400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Rep Gastroenterol"],"abstract":"<jats:p>A 27-year-old male presented with recurrent abdominal pain and high volume hematochezia despite undergoing extensive testing and a right hemicolectomy 3 years prior for a linear bleeding ulceration in the ascending colon. Studies at the University of Michigan included esophagogastroduodenoscopy (EGD), colonoscopy and video capsule endoscopy (VCE), revealing an arteriovenous malformation (AVM) in the terminal ileum. He was hospitalized for recurrent symptoms. His presentation suggested a small bowel source of obscure-overt GI bleeding based on prior non-diagnostic colonoscopy and EGD and a bilious nasogastric lavage. Tagged red blood cell scan localized bleeding to the right lower quadrant. Colonoscopy showed fresh blood in the terminal ileum without a clear source. Angiography showed no evidence of bleeding or terminal ileal AVM. A novel Meckel\u2019s scan fused with SPECT imaging showed focal uptake in the terminal ileum. The patient underwent Meckel\u2019s diverticulectomy with sparing of adjacent bowel and has remained asymptomatic for 19 months. This case illustrates that patients with obscure-overt GI bleeding require a step-wise multi-modality diagnostic work-up. Because Meckel\u2019s scans are false-positive in 28% of adults, Meckel\u2019s scan fused with SPECT imaging may offer an approach to refine diagnostic accuracy of either scan alone, but requires further investigation. Exploratory laparotomy should be reserved as a last option and is best performed with intraoperative endoscopy.<\/jats:p>","DOI":"10.1159\/000119642","type":"journal-article","created":{"date-parts":[[2008,3,14]],"date-time":"2008-03-14T11:35:25Z","timestamp":1205494525000},"page":"83-90","source":"Crossref","is-referenced-by-count":8,"title":["Possible Role of Meckel\u2019s Scan Fused with SPECT CT Imaging: Unraveling the Cause of Abdominal Pain and Obscure-Overt Gastrointestinal Bleeding"],"prefix":"10.1159","volume":"2","author":[{"given":"D.Kim","family":"Turgeon","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darren","family":"Brenner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard K.J.","family":"Brown","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew J.","family":"DiMagno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2008,3,13]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1002%2Fbjs.1800700812"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1136%2Fgut.28.1.47"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.gie.2007.05.041"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1136%2Fgut.32.7.763"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016%2F0002-9610%2876%2990043-X"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1097%2F00003072-199104000-00004"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016%2F0002-9610%2878%2990238-6"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1097%2F00003072-199606000-00012"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1572-0241.2005.41649.x"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1055%2Fs-2005-870136"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1056%2FNEJMcpc049015"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1055%2Fs-2002-35850"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.gtc.2005.08.005"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1136%2Fgut.37.2.187"}],"container-title":["Case Reports in Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/119642","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/119642","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T02:18:32Z","timestamp":1745461112000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000119642"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,3,13]]},"references-count":14,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2008,4,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000119642","archive":["Portico"],"relation":{},"ISSN":["1662-0631"],"issn-type":[{"value":"1662-0631","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,3,13]]}}}