{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T01:06:14Z","timestamp":1781139974458,"version":"3.54.1"},"reference-count":19,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2008,3,7]],"date-time":"2008-03-07T00:00:00Z","timestamp":1204848000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2008,3,7]],"date-time":"2008-03-07T00:00:00Z","timestamp":1204848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nephron Clin Pract"],"abstract":"<i>Background\/Aims:<\/i> Retroperitoneal fibrosis (RPF) is a chronic inflammatory disorder causing obstructive nephropathy and renal failure. We reviewed our management of this condition. <i>Method:<\/i> All patients with RPF treated at a single center over a 15-year period were identified. A full review of notes and computer records was undertaken. <i>Results:<\/i> Data was available on 27 patients, 3 of which were excluded from later analysis. Diagnosis was based on clinical history and cross-sectional imaging. Retroperitoneal biopsy was undertaken in 3 patients. 96% had significant renal impairment at presentation with a mean serum creatinine of 688 \u00b5mol\/l. 46% required emergency hemodialysis. All patients were treated with a combination of ureteric stents and\/or steroids with an excellent clinical response. The mean best creatinine reached by the cohort was 136 \u00b5mol\/l, and renal function remained stable in the long term. No patients required chronic dialysis. Ureteric stents were removed within 12 months and low-dose steroids were continued for a mean of 34 months. Recurrent disease was observed in 25% of patients, who all responded well to further steroid therapy. Mean duration of follow-up was 76 months. <i>Conclusions:<\/i> RPF is very effectively treated by a combination of ureteric stents and steroids, with excellent long-term results using this approach. Continued follow-up is advised because of the possibility of recurrent disease.<\/jats:p>","DOI":"10.1159\/000119715","type":"journal-article","created":{"date-parts":[[2008,3,7]],"date-time":"2008-03-07T10:47:34Z","timestamp":1204886854000},"page":"c213-c220","source":"Crossref","is-referenced-by-count":63,"title":["Successful Use of Steroids and Ureteric Stents in 24 Patients with Idiopathic Retroperitoneal Fibrosis: A Retrospective Study"],"prefix":"10.1159","volume":"108","author":[{"given":"Andrew C.","family":"Fry","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sadmeet","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Smita S.","family":"Gunda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Greg B.","family":"Boustead","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Damian C.","family":"Hanbury","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas A.","family":"McNicholas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ken","family":"Farrington","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2008,3,7]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016%2FS0140-6736%2806%2968035-5"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-2559.1984.tb02371.x"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1093%2Frheumatology%2Fkeh326"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016%2FS0002-9343%2803%2900056-1"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1038%2Fsj.ki.5002427"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1086%2F433189"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016%2FS0140-6736%2804%2916100-X"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1464-410X.2006.06210.x"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1093%2Fndt%2Fgfl228"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1053%2Fj.ajkd.2007.02.268"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1136%2Fard.2004.029793"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1136%2Fpgmj.2005.038588"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1002%2Fbjs.18004619510"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1002%2Fbjs.1800750625"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1442-2042.2005.01214.x"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1089%2F089277902320913251"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.amjmed.2003.08.033"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016%2FS0022-5347%2801%2965601-5"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1136%2Fard.60.4.427"}],"container-title":["Nephron Clinical Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/119715","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/119715","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T02:19:04Z","timestamp":1745461144000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000119715"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,3,7]]},"references-count":19,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2008,4,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000119715","archive":["Portico"],"relation":{},"ISSN":["1660-2110"],"issn-type":[{"value":"1660-2110","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,3,7]]}}}