{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T12:30:56Z","timestamp":1784118656259,"version":"3.55.0"},"reference-count":20,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2008,1,1]],"date-time":"2008-01-01T00:00:00Z","timestamp":1199145600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2008,1,1]],"date-time":"2008-01-01T00:00:00Z","timestamp":1199145600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuroepidemiology"],"published-print":{"date-parts":[[2008]]},"abstract":"<jats:p>&lt;i&gt;Background\/Aim:&lt;\/i&gt; Harmane [1-methyl-9H-pyrido(3,4-b)indole] is a tremor-producing neurotoxin. Blood harmane concentrations are elevated in essential tremor (ET) patients for unclear reasons. Potential mechanisms include increased dietary harmane intake (especially through well-cooked meat) or genetic-metabolic factors. We tested the hypothesis that meat consumption and level of meat doneness are higher in ET cases than in controls. &lt;i&gt;Methods:&lt;\/i&gt; Detailed data were collected using the Lawrence Livermore National Laboratory Meat Questionnaire. &lt;i&gt;Results:&lt;\/i&gt; Total current meat consumption was greater in men with than without ET (135.3 \u00b1 71.1 vs. 110.6 \u00b1 80.4 g\/day, p = 0.03) but not in women with versus without ET (80.6 \u00b1 50.0 vs. 79.3 \u00b1 51.0 g\/day, p = 0.76). In an adjusted logistic regression analysis in males, higher total current meat consumption was associated with ET (OR = 1.006, p = 0.04, i.e., with 10 additional g\/day of meat, odds of ET increased by 6%). Male cases had higher odds of being in the highest than lowest quartile of total current meat consumption (adjusted OR = 21.36, p = 0.001). Meat doneness level was similar in cases and controls. &lt;i&gt;Conclusion:&lt;\/i&gt; This study provides evidence of a dietary difference between male ET cases and male controls. The etiological ramifications of these results warrant additional investigation.<\/jats:p>","DOI":"10.1159\/000122333","type":"journal-article","created":{"date-parts":[[2008,4,2]],"date-time":"2008-04-02T15:56:21Z","timestamp":1207151781000},"page":"161-166","source":"Crossref","is-referenced-by-count":10,"title":["Dietary Epidemiology of Essential Tremor: Meat Consumption and Meat Cooking Practices"],"prefix":"10.1159","volume":"30","author":[{"given":"Elan D.","family":"Louis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Garrett A.","family":"Keating","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth T.","family":"Bogen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eileen","family":"Rios","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathryn M.","family":"Pellegrino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pam","family":"Factor-Litvak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2008,4,2]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1002%2Fmds.10376"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1212%2F01.WNL.0000161852.70374.01"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1002%2Fmds.870130621"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1002%2Fmds.1183"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.neuropharm.2005.08.022"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1002%2Fmds.20331"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1002%2F1531-8257%28200101%2916%3A1%3C84%3A%3AAID-MDS1010%3E3.0.CO%3B2-S"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016%2F0306-4522%2893%2990500-F"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1212%2F01.wnl.0000172352.88359.2d"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1002%2Fmds.20565"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.jada.2007.05.011"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1038%2Fsj.pcan.4500941"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.jns.2006.09.007"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1159%2F000084713"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1002%2Fmds.10395"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1002%2Fmds.1182"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1468-1331.2006.01471.x"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1002%2Fmds.21349"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1093%2Faje%2Fkwk089"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1080%2F01635588309513781"}],"container-title":["Neuroepidemiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/122333","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/122333","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T02:13:23Z","timestamp":1745460803000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000122333"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008]]},"references-count":20,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2008,5,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000122333","archive":["Portico"],"relation":{},"ISSN":["0251-5350","1423-0208"],"issn-type":[{"value":"0251-5350","type":"print"},{"value":"1423-0208","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008]]}}}