{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T17:51:05Z","timestamp":1760982665668,"version":"3.40.4"},"reference-count":7,"publisher":"S. Karger AG","issue":"Suppl. 1","license":[{"start":{"date-parts":[[2008,1,1]],"date-time":"2008-01-01T00:00:00Z","timestamp":1199145600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2008,1,1]],"date-time":"2008-01-01T00:00:00Z","timestamp":1199145600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intervirology"],"published-print":{"date-parts":[[2008]]},"abstract":"<i>Objective:<\/i> To compare 8-detector row helical computed tomography (CT) findings with histopathology in patients with hepatocellular carcinoma (HCC) who had undergone living-donor liver transplantation (LDLT). <i>Materials and Methods:<\/i> This institutional review board-approved prospective study was performed between February 12, 2003 and November 12, 2004; of the 78 candidates for LDLT due to HCC who underwent preoperative multidetector CT (MDCT), 48 transplant recipients met our criteria and in 41 of them, HCCs were diagnosed with <15 lesions on MDCT; these patients represented the study population. Results of preoperative CT were correlated with histopathological results after 5-mm sagittal slicing of the explanted liver. Following the injection of contrast medium (2 ml\/kg body weight of 300 mg I\/ml), triple-phase contrast-enhanced images were obtained. CT was performed using the following parameters: detector row configuration, 8 \u00d7 1 mm, reconstruction interval, 1 mm, 200 mA s and 120 kVp. Image analysis was performed in consensus by three abdominal radiologists using 1-mm-thick slices with 0.5-mm overlap with paging as well as multiplanar reformatting (MPR; i.e. axial, coronal and sagittal images). <i>Results:<\/i> A total of 134 HCCs were identified by pathological examination. The mean lesion size was 21 mm. Sensitivity, positive predictive value and accuracy for HCC detection were 87, 96 and 84% for all lesions, respectively, and 99, 100 and 97% for lesions >1 cm, respectively, but only 46, 76 and 41% for tumors <1 cm, respectively (n = 28). There were 12 false-negative lesions but only 5 false-positive findings. <i>Conclusion:<\/i> MDCT combined with the paging method and MPR images is very effective in the detection of HCCs >1 cm in diameter with a very low false-positive rate.<\/jats:p>","DOI":"10.1159\/000122597","type":"journal-article","created":{"date-parts":[[2008,6,11]],"date-time":"2008-06-11T13:30:10Z","timestamp":1213191010000},"page":"46-51","source":"Crossref","is-referenced-by-count":10,"title":["Hepatocellular Carcinoma in Patients Undergoing Living-Donor Liver Transplantation"],"prefix":"10.1159","volume":"51","author":[{"given":"Yoji S.","family":"Maetani","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mikiko","family":"Ueda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hironori","family":"Haga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyoshi","family":"Isoda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasutsugu","family":"Takada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shigeki","family":"Arizono","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuusuke","family":"Hirokawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kootaro","family":"Shimada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshiya","family":"Shibata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Togashi","family":"Kaori","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2008,6,10]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1002%2Flt.20642"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1002%2Flt.21281"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1148%2Fradiol.2262011967"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1148%2Fradiol.2373041364"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1148%2Fradiol.2262012043"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1097%2F00000658-200204000-00011"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1097%2F00004424-199804000-00004"}],"container-title":["Intervirology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/122597","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/122597","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T02:16:06Z","timestamp":1745460966000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000122597"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008]]},"references-count":7,"journal-issue":{"issue":"Suppl. 1","published-online":{"date-parts":[[2008,6,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000122597","archive":["Portico"],"relation":{},"ISSN":["0300-5526","1423-0100"],"issn-type":[{"type":"print","value":"0300-5526"},{"type":"electronic","value":"1423-0100"}],"subject":[],"published":{"date-parts":[[2008]]}}}