{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T04:57:21Z","timestamp":1745470641105,"version":"3.40.4"},"reference-count":8,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2008,1,1]],"date-time":"2008-01-01T00:00:00Z","timestamp":1199145600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2008,1,1]],"date-time":"2008-01-01T00:00:00Z","timestamp":1199145600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Fetal Diagn Ther"],"published-print":{"date-parts":[[2008]]},"abstract":"<jats:p>&lt;i&gt;Background:&lt;\/i&gt; Pre-eclampsia is a pregnancy-related disorder present in about 5\u20137% of all pregnancies. &lt;i&gt;CD24 &lt;\/i&gt;expression was recently reported in different diseases, while it has not yet been determined in pre-eclamptic placental tissues. &lt;i&gt;Methods:&lt;\/i&gt; We collected placental tissues from pre-eclamptic (n = 16) and healthy pregnancies (n = 16). We used the quantitative real-time PCR method with a primer-probe system for determination of &lt;i&gt;CD24&lt;\/i&gt; gene expression. &lt;i&gt;Results:&lt;\/i&gt; We measured&lt;i&gt; CD24&lt;\/i&gt; concentrations of 18.94 \u00b1 26.86 ng\/\u00b5l in the pre-eclamptic and 53.85 \u00b1 92.05 ng\/\u00b5l in the healthy placental tissues (p = 0.03). &lt;i&gt;Conclusions:&lt;\/i&gt; The quantitative real-time PCR method is suitable to determine &lt;i&gt;CD24&lt;\/i&gt; expression in placental tissues. We suppose the low expression of &lt;i&gt;CD24&lt;\/i&gt; may cause the enhanced immune reaction and could play a role in the abnormal development of placenta in pre-eclampsia.<\/jats:p>","DOI":"10.1159\/000123612","type":"journal-article","created":{"date-parts":[[2008,4,14]],"date-time":"2008-04-14T13:20:56Z","timestamp":1208179256000},"page":"263-266","source":"Crossref","is-referenced-by-count":7,"title":["Under-Expression of &lt;i&gt;CD24&lt;\/i&gt; in Pre-Eclamptic Placental Tissues Determined by Quantitative Real-Time RT-PCR"],"prefix":"10.1159","volume":"23","author":[{"given":"B\u00e1lint","family":"Nagy","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enik\u0151","family":"Berkes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbara","family":"Rig\u00f3","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zolt\u00e1n","family":"B\u00e1n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zolt\u00e1n","family":"Papp","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Petronella","family":"Hupuczi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2008,4,14]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016%2F0143-4004%2891%2990339-H"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.siny.2006.04.001"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1038%2Fsj.bjc.6600702"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1002%2Fpros.10324"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1186%2F1471-2490-6-7"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1365-2141.2003.04121.x"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.placenta.2004.09.009"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016%2F0165-0378%2896%2900954-0"}],"container-title":["Fetal Diagnosis and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/123612","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/123612","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T02:27:51Z","timestamp":1745461671000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000123612"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008]]},"references-count":8,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2008,5,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000123612","archive":["Portico"],"relation":{},"ISSN":["1015-3837","1421-9964"],"issn-type":[{"type":"print","value":"1015-3837"},{"type":"electronic","value":"1421-9964"}],"subject":[],"published":{"date-parts":[[2008]]}}}