{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T18:42:37Z","timestamp":1777920157716,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2008,4,2]],"date-time":"2008-04-02T00:00:00Z","timestamp":1207094400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2008,4,2]],"date-time":"2008-04-02T00:00:00Z","timestamp":1207094400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuroendocrinology"],"abstract":"<jats:p>The nocturnal temporal patterns of pineal N-acetyltransferase (NAT) and type II thyroxine 5\u2019-deiodinase (5\u2019-D) were compared in the same animals. Both NAT and 5\u2019-D had a similar rise to a midnight zenith with the same lag period but 5\u2019-D rose to its peak 1 h before NAT. The temporal profiles of decrease in enzyme activities were quite different, with 5\u2019-D declining long before NAT. Acute light exposure caused a rapid dramatic decrease in NAT but not in 5\u2019-D. These data suggest that different mechanisms are in involved in the decrease of these two enzyme activities. The role of the antecedent rise in 5\u2019-D activity in the nocturnal rise of NAT activity is apparently minor at most, since pretreatment with iopanoic acid completely blocked the nocturnal rise in 5\u2019-D but had no effect on the nocturnal rise in NAT nor on the acute fall in NAT from its midnight zenith after exposure to light.<\/jats:p>","DOI":"10.1159\/000125206","type":"journal-article","created":{"date-parts":[[2008,4,2]],"date-time":"2008-04-02T11:56:21Z","timestamp":1207137381000},"page":"88-92","source":"Crossref","is-referenced-by-count":12,"title":["Comparison of the Nocturnal Temporal Profiles of N-Acetyl-Transferase and Thyroxine 5\u2019-Deiodinase in Rat Pineal"],"prefix":"10.1159","author":[{"given":"Masami","family":"Murakami","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monte A.","family":"Greer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan E.","family":"Greer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Staci","family":"Hjulstad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kiyoshi","family":"Tanaka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2008,4,2]]},"container-title":["Neuroendocrinology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/125206","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000125206","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T19:22:03Z","timestamp":1777663323000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000125206"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,4,2]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000125206","archive":["Portico"],"relation":{},"ISSN":["0028-3835","1423-0194"],"issn-type":[{"value":"0028-3835","type":"print"},{"value":"1423-0194","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,4,2]]}}}