{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T04:20:55Z","timestamp":1777868455656,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","issue":"5","license":[{"start":{"date-parts":[[2008,4,15]],"date-time":"2008-04-15T00:00:00Z","timestamp":1208217600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2008,4,15]],"date-time":"2008-04-15T00:00:00Z","timestamp":1208217600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur Surg Res"],"abstract":"<jats:p>A cross-circulation model was employed in the dog in which 20 ml of blood from an iliac vein (donor) was injected immediately in exactly 60 sec into the iliac artery of the recipient animal. 1 min after soft tissue trauma to the hind leg of the donor dog, this blood caused a marked, transient vasodilatation in the perfused vascular bed. This effect was no longer demonstrable 10 min after trauma. Pretreatment of the donor dog with dimercaprol (BAL), which potentiates the effect of bradykinin, significantly potentiated and prolonged the flow-increasing effect of blood from the traumatized region. A prostaglandin inhibitor (polyphloretinphosphate; PPP) had no effect. The effect of a thioxanthene derivative (BP-400), which acts as an \u2018antiamine\u2019 was not consistent. The results indicate that soft tissue trauma to the hind leg of the dog produces a transferable vasodilator substance or substances, which can be found in the venous blood. The possibility that one of these is a kinin is discussed.<\/jats:p>","DOI":"10.1159\/000127728","type":"journal-article","created":{"date-parts":[[2008,4,17]],"date-time":"2008-04-17T05:12:51Z","timestamp":1208409171000},"page":"265-276","source":"Crossref","is-referenced-by-count":5,"title":["Vasodilator Property of Venous Blood from Trauma Region"],"prefix":"10.1159","volume":"6","author":[{"given":"J.","family":"Sandeg\u00e5rd","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.H.","family":"Lewis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Seeman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2008,4,15]]},"container-title":["European Surgical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000127728","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T11:58:26Z","timestamp":1777550306000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000127728"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,4,15]]},"references-count":0,"journal-issue":{"issue":"5","published-online":{"date-parts":[[1974,5,1]]},"published-print":{"date-parts":[[1974,5,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000127728","archive":["Portico"],"relation":{},"ISSN":["0014-312X","1421-9921"],"issn-type":[{"value":"0014-312X","type":"print"},{"value":"1421-9921","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,4,15]]}}}