{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T06:56:19Z","timestamp":1781506579009,"version":"3.54.1"},"reference-count":17,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2008,1,1]],"date-time":"2008-01-01T00:00:00Z","timestamp":1199145600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2008,1,1]],"date-time":"2008-01-01T00:00:00Z","timestamp":1199145600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dermatology"],"published-print":{"date-parts":[[2008]]},"abstract":"<jats:p>&lt;i&gt;Background:&lt;\/i&gt; Cosmetic filler injections are now a very common procedure for aesthetic purposes. Today no contra-indication is given anymore to any patient for an intradermal filling. &lt;i&gt;Objectives:&lt;\/i&gt; We draw attention to a possible side effect of facial fillers in a population at risk. &lt;i&gt;Results:&lt;\/i&gt; We report 2 similar cases of systemic sarcoidosis in patients who both developed a sarcoidal granuloma at the location of a cosmetic filler injection during combined interferon and ribavirin treatment for chronic hepatitis C infection. Cosmetic fillers were hyaluronic acid for one patient and probably silicone for the other. &lt;i&gt;Conclusion:&lt;\/i&gt; Patients with chronic hepatitis C have a higher risk of interferon-induced sarcoidosis. Physicians must be aware of the risk that a granuloma can develop after a dermal filler injection especially in patients treated with interferon for chronic hepatitis C. These reactions may reveal a systemic sarcoidosis. We propose to perform a test for a hepatitis C virus infection before injecting a dermal filler and to inform the patient of this risk in case of a hepatitis C infection that could necessitate an interferon treatment.<\/jats:p>","DOI":"10.1159\/000128281","type":"journal-article","created":{"date-parts":[[2008,4,28]],"date-time":"2008-04-28T09:25:28Z","timestamp":1209374728000},"page":"81-84","source":"Crossref","is-referenced-by-count":50,"title":["Facial Cosmetic Filler Injections as Possible Target for Systemic Sarcoidosis in Patients Treated with Interferon for Chronic Hepatitis C: Two Cases"],"prefix":"10.1159","volume":"217","author":[{"given":"Vincent","family":"Descamps","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Landry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camille","family":"Franc\u00e8s","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo","family":"Marinho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vlad","family":"Ratziu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivier","family":"Chosidow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2008,4,29]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hoc.2011.03.014"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-444-52138-5.00010-4"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.24885"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1007\/s11605-012-1941-3"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-1318.2011.02588.x"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1007\/BF02984628"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1007\/s11307-007-0117-0"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbmt.2006.11.003"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2008-07-170449"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.beha.2005.07.008"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1155\/2010\/164045"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0609.2007.00840.x"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.3109\/03630260903546445"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1038\/bmt.2009.188"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdj057"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1097\/00130404-200509000-00010"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1093\/jjco\/hys005"}],"container-title":["Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/128281","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/128281","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T01:16:46Z","timestamp":1745457406000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000128281"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008]]},"references-count":17,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2008,6,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000128281","archive":["Portico"],"relation":{},"ISSN":["1018-8665","1421-9832"],"issn-type":[{"value":"1018-8665","type":"print"},{"value":"1421-9832","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008]]}}}