{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T22:47:27Z","timestamp":1777762047900,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2008,4,30]],"date-time":"2008-04-30T00:00:00Z","timestamp":1209513600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2008,4,30]],"date-time":"2008-04-30T00:00:00Z","timestamp":1209513600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cytogenetics"],"abstract":"<jats:p>The chromosomes of 344 early chick embryos (16 to 18 h of incubation) were examined. These embryos were derived from two related lines of broiler-type stock, a line selected for rapid growth rate and a companion line that had been random bred as controls. Of the 344 embryos examined, 282 were obtained from the rapid growth line and 62 from the random-bred controls. A high frequency, 38 of 344, or 11.0%, of these embryos were found to be either entirely or partially composed of cells with abnormal karyotypes. The frequencies of these abnormal embryos in the two lines were 36 of 282(12.7%) in the rapid growth line and 2 of 62 (3.2%) in the control line. Abnormalities observed included: one case of a trisomic\/monosomic mosaic involving chromosome No. 1, two haploid embryos, four triploid embryos, four haploid\/triploid mosaics, seven haploid\/diploid mosaics, sixteen diploid\/tetraploid mosaics, one haploid\/ diploid\/tetraploid mosaic, one haploid\/diploid\/tetraploid\/octaploid mosaic, one diploid\/ tetraploid mosaic which also involved sex-chromosome aneuploidy (2A\/4A with ZZW\/ZZZZWW), and one case of chromosomal rearrangement. Examination of the pedigrees of the abnormal embryos revealed that several mating pairs had produced a number of embryos with similar abnormalities.<\/jats:p>","DOI":"10.1159\/000130134","type":"journal-article","created":{"date-parts":[[2008,4,30]],"date-time":"2008-04-30T05:35:09Z","timestamp":1209533709000},"page":"121-136","source":"Crossref","is-referenced-by-count":24,"title":["Chromosome abnormalities in 16- to 18-hour chick embryos"],"prefix":"10.1159","author":[{"given":"R.C.","family":"Miller","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.S.","family":"Fechheimer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.G.","family":"Japp","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2008,4,30]]},"container-title":["Cytogenetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/130134","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000130134","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T14:25:05Z","timestamp":1777472705000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000130134"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,4,30]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000130134","archive":["Portico"],"relation":{},"ISSN":["0011-4537"],"issn-type":[{"value":"0011-4537","type":"print"}],"subject":[],"published":{"date-parts":[[2008,4,30]]}}}