{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T18:33:05Z","timestamp":1791397985190,"version":"4.3.3"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2008,5,14]],"date-time":"2008-05-14T00:00:00Z","timestamp":1210723200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2008,5,14]],"date-time":"2008-05-14T00:00:00Z","timestamp":1210723200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cytogenet Cell Genet"],"abstract":"<jats:p>Human sperm chromosomes were studied in a man heterozygous for a pericentric inversion (p23q22) of chromosome 8. The pronuclear chromosomes were analyzed after in vitro penetration of golden hamster eggs. A total of 166 sperm were examined; 88.6% were chromosomally balanced and 11.4% were recombinant. Of the balanced complements, the proportion with a normal chromosome 8 (53.6%) was approximately equal to the proportion with an inverted 8 (46.4%). Of the recombinant complements, the proportion of sperm with a duplication of 8q and a deletion of 8p (5.7%) was equal to the reciprocal event of a duplication of 8p and a deletion of 8q (5.7%). The frequencies of X-bearing (53.2%) and Y-bearing sperm (46.8%) were not significantly different from the expected 1:1 ratio. There was no evidence for an interchromosomal effect. A total of four pericentric inversions have been studied by human sperm chromosome analysis; recombinant chromosomes have been observed in two of the four cases.<\/jats:p>","DOI":"10.1159\/000133475","type":"journal-article","created":{"date-parts":[[2008,5,16]],"date-time":"2008-05-16T08:10:54Z","timestamp":1210925454000},"page":"199-202","source":"Crossref","is-referenced-by-count":16,"title":["Analysis of sperm chromosome complements from a man heterozygous for a pericentric inversion, inv(8)(p23q22)"],"prefix":"10.1159","author":[{"given":"R.H.","family":"Martin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2008,5,14]]},"container-title":["Cytogenetics and Cell Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/133475","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000133475","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T14:59:15Z","timestamp":1777474755000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000133475"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,5,14]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000133475","archive":["Portico"],"relation":{},"ISSN":["0301-0171","1421-9816"],"issn-type":[{"value":"0301-0171","type":"print"},{"value":"1421-9816","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,5,14]]}}}