{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T01:51:10Z","timestamp":1777945870266,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2008,5,28]],"date-time":"2008-05-28T00:00:00Z","timestamp":1211932800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2008,5,28]],"date-time":"2008-05-28T00:00:00Z","timestamp":1211932800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pharmacology"],"abstract":"<jats:p>The effects of intra-arterially (i.a.) injected morphine and dextromoramide on 5-hydroxytryptamine (5-HT)-induced contrac tion of the jejunum of dog were tested. Dextromoramide increased the intestinal contractile action of 5-HT from 44.7 \u00b1 8.8 cm H&lt;sub&gt;2&lt;\/sub&gt;\u00b7to 154.6 \u00b1 17.3 cm H&lt;sub&gt;2&lt;\/sub&gt;O. This effect was reversible in about 15 min. The tryptamine antagonists LSD, BOL, dibenamine, and cyproheptadine failed in blocking 5-HT and the narcotic analgesics. Atropine (50 \u00b5g\/kg i.a.), however, was active in this respect. We propose that 5-HT released by morphine acts on tryptamine receptors located on the ganglionar cells and is not blocked by LSD. Possibly morphine inhibits also the uptake of 5-HT by the myenteric plexus which would explain the potentiation of exogenous 5-HT.<\/jats:p>","DOI":"10.1159\/000136449","type":"journal-article","created":{"date-parts":[[2008,5,30]],"date-time":"2008-05-30T03:28:44Z","timestamp":1212118124000},"page":"291-297","source":"Crossref","is-referenced-by-count":2,"title":["Interactions of 5-Hydroxytryptamine and Narcotic Analgesics on Dog Intestine in vivo"],"prefix":"10.1159","author":[{"given":"L.F.","family":"de Oliveira","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Sollero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2008,5,28]]},"container-title":["Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000136449","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T13:31:59Z","timestamp":1777728719000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000136449"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,5,28]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000136449","archive":["Portico"],"relation":{},"ISSN":["0031-7012","1423-0313"],"issn-type":[{"value":"0031-7012","type":"print"},{"value":"1423-0313","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,5,28]]}}}