{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T01:55:45Z","timestamp":1777946145577,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2008,6,4]],"date-time":"2008-06-04T00:00:00Z","timestamp":1212537600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2008,6,4]],"date-time":"2008-06-04T00:00:00Z","timestamp":1212537600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pharmacology"],"abstract":"<jats:p>Effects of prostaglandin E&lt;sub&gt;2&lt;\/sub&gt; (PGE&lt;sub&gt;2&lt;\/sub&gt;) and cholinergic drugs on intraocular pressure (IOP) have been studied in the rabbit. PGE&lt;sub&gt;2&lt;\/sub&gt; injected intracamerally in a dose of 5 \u00b5g produced a long-lasting increase in IOP. Topical pretreatment with carbachol, physostigmine and pilo-carpine abolished the rise of IOP after the intracameral injection of PGE&lt;sub&gt;2&lt;\/sub&gt;. When the IOP had already been increased by PGE&lt;sub&gt;2&lt;\/sub&gt; topical application of pilocarpine and physostigmine did not change it. Carbachol even potentiated the pressor effect of PGE&lt;sub&gt;2&lt;\/sub&gt;.<\/jats:p>","DOI":"10.1159\/000137736","type":"journal-article","created":{"date-parts":[[2008,6,5]],"date-time":"2008-06-05T03:36:29Z","timestamp":1212636989000},"page":"149-153","source":"Crossref","is-referenced-by-count":0,"title":["Effects of Prostaglandin E\n                    <sub>2<\/sub>\n                    and Cholinergic Drugs on Intraocular Pressure"],"prefix":"10.1159","author":[{"given":"S.","family":"Golubovi\u0107","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.\u017d.","family":"Radmanovi\u0107","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2008,6,4]]},"container-title":["Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000137736","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T15:46:36Z","timestamp":1777736796000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000137736"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,6,4]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000137736","archive":["Portico"],"relation":{},"ISSN":["0031-7012","1423-0313"],"issn-type":[{"value":"0031-7012","type":"print"},{"value":"1423-0313","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,6,4]]}}}