{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T04:52:21Z","timestamp":1745470341506,"version":"3.40.4"},"reference-count":0,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[1983,1,1]],"date-time":"1983-01-01T00:00:00Z","timestamp":410227200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[1983,1,1]],"date-time":"1983-01-01T00:00:00Z","timestamp":410227200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cells Tissues Organs"],"published-print":{"date-parts":[[1983]]},"abstract":"<jats:p>The ultrastructure of splenic cells and frequency of cell types were examined in fetal rats during progesterone-induced (P23, 24, 25) and surgically-induced (S23, 24, 25) prolonged gestation, and compared to term (T) fetuses and newborn animals (N&lt;sub&gt;1&lt;\/sub&gt; N&lt;sub&gt;2&lt;\/sub&gt;, N&lt;sub&gt;3&lt;\/sub&gt;). Statistical analysis revealed an increase in numbers of erythroblasts and a decrease in numbers of neutrophils in post-term fetuses distinct from that seen in term and newborn animals. However, there were also significant differences between the post-term groups: the frequency of erythrocytes and total number of cells were higher in the drug-treated group, despite similar splenic weights in the two. The results are interpreted as a response by the spleen (increased erythropoiesis) to fetal hypoxia, which is known to exist during prolonged gestation.<\/jats:p>","DOI":"10.1159\/000145792","type":"journal-article","created":{"date-parts":[[2008,7,11]],"date-time":"2008-07-11T14:40:38Z","timestamp":1215787238000},"page":"231-238","source":"Crossref","is-referenced-by-count":1,"title":["Morphological Observations of the Fetal Rat Spleen during Prolonged Gestation"],"prefix":"10.1159","volume":"117","author":[{"given":"James A.","family":"Thliveris","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniela","family":"Petriuk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judy E.","family":"Anderson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edmund E.","family":"Faridy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2008,7,11]]},"container-title":["Cells Tissues Organs"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/145792","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/145792","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T00:40:51Z","timestamp":1745455251000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000145792"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1983]]},"references-count":0,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2004,7,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000145792","archive":["Portico"],"relation":{},"ISSN":["1422-6405","1422-6421"],"issn-type":[{"type":"print","value":"1422-6405"},{"type":"electronic","value":"1422-6421"}],"subject":[],"published":{"date-parts":[[1983]]}}}