{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T14:31:44Z","timestamp":1774881104207,"version":"3.50.1"},"reference-count":38,"publisher":"S. Karger AG","issue":"3-4","license":[{"start":{"date-parts":[[2008,1,1]],"date-time":"2008-01-01T00:00:00Z","timestamp":1199145600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2008,1,1]],"date-time":"2008-01-01T00:00:00Z","timestamp":1199145600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Oncology"],"published-print":{"date-parts":[[2008]]},"abstract":"<jats:p>&lt;i&gt;Background:&lt;\/i&gt; We assessed longevity and complications of totally implantable venous access devices in oncology patients. &lt;i&gt;Methods:&lt;\/i&gt; 197 patients received a total of 201 port devices via the subclavian vein for delivery of chemotherapy between January 1, 2005, and December 31, 2006. We reviewed the patient charts for port-related complications and risk factors until July 31, 2007. &lt;i&gt;Results:&lt;\/i&gt;A total of 47,781 catheter days were analyzed (median, 175 days; range, 1\u2013831). Forty-six different complications occurred (0.96 complications\/1,000 catheter days). The only risk factor significantly associated with a higher complication rate was younger age. Older patients had a lower risk for developing complications with a risk reduction of 2.4% for each year. There were no differences regarding underlying tumor, gender, access side, method of placement (subclavian\/cephalic vein) or implanting team (thoracic versus visceral surgery). A trend was seen for shorter port longevity in hematologic patients compared to oncologic patients (p = 0.059). The former developed significantly more port-associated infections than solid tumor patients [11\/53 cases (21%) versus 2\/148 cases (1.4%); p &lt; 0.0001]. &lt;i&gt;Conclusions:&lt;\/i&gt; Port-associated infections were mostly observed in younger patients with hematologic neoplasms. Prospective trials should be performed to evaluate the benefit of a prophylactic antimicrobial lock in these selected patients.<\/jats:p>","DOI":"10.1159\/000151393","type":"journal-article","created":{"date-parts":[[2008,8,20]],"date-time":"2008-08-20T10:03:01Z","timestamp":1219226581000},"page":"237-244","source":"Crossref","is-referenced-by-count":52,"title":["Infectious Port Complications Are More Frequent in Younger Patients with Hematologic Malignancies than in Solid Tumor 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