{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T20:34:00Z","timestamp":1762979640455},"reference-count":11,"publisher":"S. Karger AG","issue":"5","license":[{"start":{"date-parts":[[2008,1,1]],"date-time":"2008-01-01T00:00:00Z","timestamp":1199145600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2008,1,1]],"date-time":"2008-01-01T00:00:00Z","timestamp":1199145600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur Neurol"],"published-print":{"date-parts":[[2008]]},"abstract":"<jats:p>&lt;i&gt;Background:&lt;\/i&gt; In neurally mediated syncope a \u2018typical\u2019 EEG pattern during hyperventilation (HV) may be observed. This study aimed to investigate transcranial Doppler (TCD) and EEG variations in response to hyper- and hypocapnia using simultaneous recording. &lt;i&gt;Methods:&lt;\/i&gt; Syncope patients with a typical EEG pattern during HV (SEEG+, n = 15) and those without abnormalities (SEEG\u2013, n = 16) were compared with healthy controls (n = 20). Simultaneous TCD and EEG recordings were performed at rest (baseline), during 2 apnea tests and during HV. Cerebrovascular vasoreactivity, index for hypocapnia, total vasomotor reserve and time to flow velocity normalization after HV (t-norm) were recorded. &lt;i&gt;Results:&lt;\/i&gt; With TCD, a reduction in Vasomotor reserve was observed in SEEG+ compared with the other 2 groups (control: 67 \u00b1 8%; SEEG\u2013: 67 \u00b1 10%; SEEG+: 57 \u00b1 8%; p &lt; 0.0001). t-norm was longer in all syncopal patients and in particular in SEEG+ (control: 20.2 \u00b1 3 s; SEEG\u2013: 40 \u00b1 7 s; SEEG+: 123 \u00b1 45s; p &lt; 0.0001). Quantitative EEG showed an increase in slow bands in all subjects during HV, small and nonsignificant in controls and SEEG\u2013, higher and significant in SEEG+, related with flow reduction. &lt;i&gt;Conclusions:&lt;\/i&gt; Changes in the sympathetic modulation of cerebral vasoconstriction may explain both the pathophysiology of vasovagal syncope and the typical paroxysmal EEG findings.<\/jats:p>","DOI":"10.1159\/000151702","type":"journal-article","created":{"date-parts":[[2008,9,1]],"date-time":"2008-09-01T12:12:12Z","timestamp":1220271132000},"page":"258-263","source":"Crossref","is-referenced-by-count":5,"title":["Combined Transcranial Doppler and EEG Recording in Vasovagal Syncope"],"prefix":"10.1159","volume":"60","author":[{"given":"E.","family":"Vicenzini","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Pro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Strano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Pulitano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Altieri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"Di Piero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.L.","family":"Lenzi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Accornero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O.","family":"Mecarelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2009,8,29]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016%2FS0140-6736%2800%2903642-4"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1002%2Fana.410360217"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.yebeh.2005.01.003"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.neucli.2004.09.004"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1097%2F00004691-198704000-00001"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1161%2Fhc6172.099397"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1007%2FBF02267722"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.3171%2Fjns.1986.65.3.0335"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1097%2F00002826-200109000-00005"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1097%2F00004691-199705000-00004"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016%2FS0140-6736%2857%2992147-5"}],"container-title":["European Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/151702","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/151702","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,12]],"date-time":"2024-09-12T20:12:34Z","timestamp":1726171954000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/ENE\/article\/doi\/10.1159\/000151702"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008]]},"references-count":11,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2008,10,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000151702","archive":["Portico"],"relation":{},"ISSN":["0014-3022","1421-9913"],"issn-type":[{"type":"print","value":"0014-3022"},{"type":"electronic","value":"1421-9913"}],"subject":[],"published":{"date-parts":[[2008]]}}}