{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T07:08:23Z","timestamp":1790752103709,"version":"4.1.0"},"reference-count":10,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2008,1,1]],"date-time":"2008-01-01T00:00:00Z","timestamp":1199145600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2008,1,1]],"date-time":"2008-01-01T00:00:00Z","timestamp":1199145600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuropsychobiology"],"published-print":{"date-parts":[[2008]]},"abstract":"<jats:p>\u03b1-Synuclein (\u03b1-Syn) is a neuronal protein involved in the regulation of brain serotonin and dopamine levels. We analyzed the peripheral expression of \u03b1-Syn mRNA and Beck Depression Inventory scores in female patients suffering from anorexia nervosa (n = 18) or bulimia nervosa (n = 24). We found a significant positive association between \u03b1-Syn mRNA expression and the total scores of the Beck Depression Inventory (linear regression; R&lt;sup&gt;2&lt;\/sup&gt; = 0.20; p = 0.003). \u03b1-Syn may play a pathophysiological role in depressive symptoms associated with eating disorders. Further investigations in patients with depression as a sole diagnosis are needed to support its role in the pathogenesis of major depression.<\/jats:p>","DOI":"10.1159\/000155991","type":"journal-article","created":{"date-parts":[[2008,10,3]],"date-time":"2008-10-03T05:49:01Z","timestamp":1223012941000},"page":"48-52","source":"Crossref","is-referenced-by-count":15,"title":["Alpha-Synuclein mRNA Levels Correspond to Beck Depression Inventory Scores in Females with Eating Disorders"],"prefix":"10.1159","volume":"58","author":[{"given":"Helge","family":"Frieling","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Gozner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konstanze D.","family":"R\u00f6mer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia","family":"Wilhelm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Hillemacher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes","family":"Kornhuber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martina","family":"de Zwaan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georg E.","family":"Jacoby","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Bleich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2008,9,18]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016%2FS0272-7358%2802%2900201-5"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1038%2Fsj.mp.4001931"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1460-9568.2006.04900.x"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1007%2Fs10024-003-7080-9"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1007%2Fs00702-005-0315-3"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1001%2Farchpsyc.1961.01710120031004"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.biopsych.2004.09.016"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.biopsych.2005.09.018"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016%2FS0893-133X%2899%2900053-6"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016%2F0022-3999%2894%2990030-2"}],"container-title":["Neuropsychobiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/155991","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/155991","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T01:08:06Z","timestamp":1745456886000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000155991"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008]]},"references-count":10,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2008,10,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000155991","archive":["Portico"],"relation":{},"ISSN":["0302-282X","1423-0224"],"issn-type":[{"value":"0302-282X","type":"print"},{"value":"1423-0224","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008]]}}}