{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T06:03:37Z","timestamp":1777615417341,"version":"3.51.4"},"reference-count":19,"publisher":"S. Karger AG","issue":"5","license":[{"start":{"date-parts":[[2008,1,1]],"date-time":"2008-01-01T00:00:00Z","timestamp":1199145600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2008,1,1]],"date-time":"2008-01-01T00:00:00Z","timestamp":1199145600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Stereotact Funct Neurosurg"],"published-print":{"date-parts":[[2008]]},"abstract":"<i>Objective:<\/i> To investigate the short-term psychological function of opiate addicts who have undergone ablative stereotactic surgery targeting the nucleus accumbens (NAc) for alleviating opiate drug psychological dependence. <i>Methods:<\/i> The psychological functional status of 14 opiate addicts was assessed by standardized psychological tests both before and approximately 3 months after stereotactic surgery. Standardized tests included the Wechsler Adult Intelligence Scale-Revised Chinese (WAIS-RC), the Clinical Memory Scale of Chinese (CMS), the Eysenck Personality Questionnaire (EPQ) and the Symptom Checklist 90 (SCL-90). The evaluation of psychological dimensions included intelligence, memory, personality characteristics and mental health symptoms. <i>Results:<\/i> Compared with the preoperative state, there was no statistically significant difference in full-scale intelligence quotient (IQ) postoperatively, but without Bonferroni correction a significant decline by 13.55% (p < 0.05) was observed in the Digit Symbol-Substitution subtest of WAIS-RC. The memory quotient (MQ) of CMS demonstrated a significant decline of 10.65% (p < 0.05) postoperatively. Concerning the participants\u2019 personality characteristics, a significant postoperative increase (p < 0.05) was detected in the Psychoticism (P) trait of EPQ. The mental healthy severity indexes of SCL-90 were decreased postoperatively. After Bonferroni correction, however, there was no statistical difference between pre- and postoperative results on all assessments. <i>Conclusions:<\/i> Although the patients\u2019 intelligence measures were not changed significantly, their short-term memory and attention appeared to decline postoperatively. In addition, there was a trend towards change in some personality characteristics postoperatively. The postoperative mental health levels of the patients increased, indicating a trend towards improvement. Stereotactic ablation of the NAc in opiate addicts may be associated with short-term negative psychological functions. Advisement regarding the safety of the new surgical modality and recommendations for further investigation are necessary.<\/jats:p>","DOI":"10.1159\/000160155","type":"journal-article","created":{"date-parts":[[2008,10,20]],"date-time":"2008-10-20T07:39:40Z","timestamp":1224488380000},"page":"320-329","source":"Crossref","is-referenced-by-count":13,"title":["Evaluation of Short-Term Psychological Functions in Opiate Addicts after Ablating the Nucleus Accumbens via Stereotactic Surgery"],"prefix":"10.1159","volume":"86","author":[{"given":"Fei","family":"He","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hao","family":"Guan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhijing","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinfang","family":"Miao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qin","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lihong","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dongmei","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anheng","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Danmin","family":"Miao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2008,10,8]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1159%2F000102404"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1159%2F000075111"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.3109%2F00207459008985956"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1192%2Fbjp.128.3.280"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.archger.2006.05.001"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1007%2Fs00213-006-0510-4"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.neuropharm.2003.11.011"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1073%2Fpnas.92.26.12304"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016%2F0165-6147%2892%2990060-J"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1007%2Fs002130050169"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1080%2F13554790600646995"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016%2F0165-0173%2893%2990013-P"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1097%2F01.yco.0000218594.46431.2f"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1177%2F1073858406295854"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.paid.2003.10.010"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016%2FS0191-8869%2803%2900082-5"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.neuroimage.2005.12.048"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.paid.2004.04.017"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016%2F0191-8869%2894%2990289-5"}],"container-title":["Stereotactic and Functional Neurosurgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/160155","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/160155","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T00:41:05Z","timestamp":1745455265000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000160155"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008]]},"references-count":19,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2008,10,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000160155","archive":["Portico"],"relation":{},"ISSN":["1011-6125","1423-0372"],"issn-type":[{"value":"1011-6125","type":"print"},{"value":"1423-0372","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008]]}}}