{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T17:37:02Z","timestamp":1792517822621,"version":"4.5.0"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2008,10,7]],"date-time":"2008-10-07T00:00:00Z","timestamp":1223337600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2008,10,7]],"date-time":"2008-10-07T00:00:00Z","timestamp":1223337600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pathol Microbiol (Basel)"],"abstract":"<jats:p>In aging hypopituitary dwarf mice (dwdw), articular chondrocytes are poorly supplied with organelles; aggregation of collagen in the cartilaginous matrix is decreased, and aging of the articular cartilage is retarded as compared to non-dwarf mice (Dwdw or DwDw) of the same strain. Osteoarthrosis developing in 58% of male and in 22 % of female non-dwarfs was not observed in dwarfs regardless of sex. The unusually long life span of dwarf mice suggests that in hypopituitarism aging of non-skeletal tissues is likewise retarded.<\/jats:p>","DOI":"10.1159\/000162458","type":"journal-article","created":{"date-parts":[[2008,10,11]],"date-time":"2008-10-11T16:33:17Z","timestamp":1223742797000},"page":"417-430","source":"Crossref","is-referenced-by-count":9,"title":["Articular Aging and Osteoarthrosis in Dwarf Mice"],"prefix":"10.1159","author":[{"given":"Ruth","family":"Silberberg","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2008,10,7]]},"container-title":["Pathologia et Microbiologia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/162458","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000162458","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T12:00:17Z","timestamp":1777723217000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000162458"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,10,7]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000162458","archive":["Portico"],"relation":{},"ISSN":["0031-2959","2235-168X"],"issn-type":[{"value":"0031-2959","type":"print"},{"value":"2235-168X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,10,7]]}}}