{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T01:45:55Z","timestamp":1777945555690,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2008,10,7]],"date-time":"2008-10-07T00:00:00Z","timestamp":1223337600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2008,10,7]],"date-time":"2008-10-07T00:00:00Z","timestamp":1223337600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Exp Cell Biol"],"abstract":"<jats:p>Hepatic granulomas of euthymic (nu\/+) mice infected with Schistosoma mansoni were freeze-dried or freeze-thawed 3 times and transplanted subcutaneously into naive nu\/+ and athymic (nu\/nu) mice. The grafted sites, studied histologically, showed formation of organized granulomas in nu\/+ mice similar to donor granulomas as observed after grafting of freshly isolated granulomas. On the other hand, in nu\/nu mice, the nonviable transplants elicited small and disorganized granulomas, like hepatic granulomas in nu\/nu mice with schistosomiasis, but different from fresh nu\/+ transplants in nu\/nu skin. The findings indicate viable cells are not required for transfer of granulomatous reactions, but T cells are needed for full expression.<\/jats:p>","DOI":"10.1159\/000163414","type":"journal-article","created":{"date-parts":[[2008,10,20]],"date-time":"2008-10-20T03:39:40Z","timestamp":1224473980000},"page":"173-178","source":"Crossref","is-referenced-by-count":0,"title":["Transfer of Granulomatous Inflammation with Nonviable Preparations of Schistosome Granulomas in Naive Mice"],"prefix":"10.1159","author":[{"given":"Mitsuse","family":"Okamoto","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William L.","family":"Epstein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideko","family":"Suya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazunori","family":"Kanazawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kimie","family":"Fukuyama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2008,10,7]]},"container-title":["Experimental Cell Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/163414","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000163414","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T12:23:49Z","timestamp":1777724629000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000163414"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,10,7]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000163414","archive":["Portico"],"relation":{},"ISSN":["0304-3568","2235-1671"],"issn-type":[{"value":"0304-3568","type":"print"},{"value":"2235-1671","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,10,7]]}}}