{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T00:54:50Z","timestamp":1777769690134,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2008,10,29]],"date-time":"2008-10-29T00:00:00Z","timestamp":1225238400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2008,10,29]],"date-time":"2008-10-29T00:00:00Z","timestamp":1225238400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiology"],"abstract":"<jats:p>54 patients with chronic atrial fibrillation were randomly divided into two groups and treated respectively with practolol and quinidine (26 cases) and with placebo and quinidine (28 cases). Sinus rhythm was restored in about the same percentage of cases in the two groups (42.3 and 46.4%). This suggests the following conclusions: practolol is devoid of therapeutic activity in the treatment of chronic atrial fibrillation; in agreement with similar observations made with other \u03b2-adrenergic blocking agents (propranolol, LB 46, and alprenolol), practolol seems to protect the myocardium from the onset of severe ventricular arrhythmia during the course of quinidine therapy.<\/jats:p>","DOI":"10.1159\/000169654","type":"journal-article","created":{"date-parts":[[2008,10,31]],"date-time":"2008-10-31T11:35:40Z","timestamp":1225452940000},"page":"364-368","source":"Crossref","is-referenced-by-count":8,"title":["Double-Blind Evaluation of Practolol and Quinidine in the Treatment of Chronic Atrial Fibrillation"],"prefix":"10.1159","author":[{"given":"G.","family":"Levi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Proto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Rovetta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2008,10,29]]},"container-title":["Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000169654","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T16:21:26Z","timestamp":1777479686000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000169654"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,10,29]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000169654","archive":["Portico"],"relation":{},"ISSN":["0008-6312","1421-9751"],"issn-type":[{"value":"0008-6312","type":"print"},{"value":"1421-9751","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,10,29]]}}}