{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T00:57:32Z","timestamp":1777769852794,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2008,10,31]],"date-time":"2008-10-31T00:00:00Z","timestamp":1225411200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2008,10,31]],"date-time":"2008-10-31T00:00:00Z","timestamp":1225411200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiology"],"abstract":"<jats:p>Exercise thallium-201 (201Tl) myocardial scans were obtained in 102 patients undergoing diagnostic coronary arteriography, of whom 59 showed more than 70% narrowing of one or more of the coronary arteries, 8 showed 50\u201370% narrowing of one vessel, and 35 had normal coronary arteriograms. Among the 59 patients with coronary artery disease, the exercise ECG was positive in 33 (55%) and the exercise 201Tl was abnormal in 45 (76%). 52 of these 59 patients (91%) had either an abnormal exercise 201Tl or a positive exercise ECG or both (p &lt; 0.001 compared to exercise ECG). The exercise ECG was inconclusive in 17 patients and among those, the exercise 201Tl correctly identified 13 cases (76%). Of 29 patients with a normal left ventriculogram, 17 (58%) showed abnormal exercise 201Tl, 28 of 30 patients (93%) with abnormal left ventriculograms showed an abnormal myocardial scan (p &lt; 0.05). 23 of 25 patients (92%) with collateral circulation had abnormal exercise 201Tl compared with 22 of 34 patients (64%) without collateral circulation (p &lt; 0.05). Among 35 patients with normal coronary arteriogram, 5 (15%) had abnormal exercise 201Tl; 4 of them also had positive exercise ECGs, and 2 showed prolapse of the mitral valve angiographically. 14 patients in this group had inconclusive exercise ECGs; and the exercise 201Tl correctly identified 13 of them (92%). We conclude that (1) exercise 201Tl improves the diagnostic value of exercise ECG; (2) the left ventriculogram and collateral circulation show a significant correlation with the incidence of abnormal exercise 201Tl; (3) false-negative exercise 201 Tl is observed predominantly in patients with disease limited to the secondary branches of the left coronary system, and (4) false-positive exercise 201Tl can be encountered in patients with prolapse of the mitral valve and with normal coronary arteriograms.<\/jats:p>","DOI":"10.1159\/000170804","type":"journal-article","created":{"date-parts":[[2008,11,4]],"date-time":"2008-11-04T03:27:32Z","timestamp":1225769252000},"page":"136-152","source":"Crossref","is-referenced-by-count":4,"title":["Exercise Thallium-201 Myocardial Scintigraphy: Advantages and Limitations"],"prefix":"10.1159","author":[{"given":"Abdulmassih S.","family":"Iskandrian","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gary S.","family":"Mintz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Millard N.","family":"Croll","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Wallner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles E.","family":"Bemis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Demetrios","family":"Kimbiri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernard L.","family":"Segal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2008,10,31]]},"container-title":["Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000170804","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T16:24:13Z","timestamp":1777479853000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000170804"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,10,31]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000170804","archive":["Portico"],"relation":{},"ISSN":["0008-6312","1421-9751"],"issn-type":[{"value":"0008-6312","type":"print"},{"value":"1421-9751","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,10,31]]}}}