{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T13:13:31Z","timestamp":1774703611362,"version":"3.50.1"},"reference-count":19,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2008,11,15]],"date-time":"2008-11-15T00:00:00Z","timestamp":1226707200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2008,11,15]],"date-time":"2008-11-15T00:00:00Z","timestamp":1226707200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cerebrovasc Dis"],"published-print":{"date-parts":[[2009]]},"abstract":"<jats:p>&lt;i&gt;Background:&lt;\/i&gt; Few studies have addressed predictors of long-term mortality after first-ever ischaemic stroke. &lt;i&gt;Methods:&lt;\/i&gt; We prospectively collected data on 361 consecutive patients admitted to 18 neurology departments in Italy for a first-ever ischaemic stroke in 1999, categorized according to the Oxfordshire Community Stroke Project (OCSP) classification. Age, gender, risk factors, previous vascular disease, in-hospital complications, stroke severity, functional status, therapy and living place at admission, discharge and after 6 months were recorded. Follow-up was available for 97% patients at 5 years. &lt;i&gt;Results:&lt;\/i&gt; Survival probability was 91% (95% CI = 88\u201394) at 1 month, 84% (80\u201388) at 6 months and 64% (58\u201369) at 5 years. Mortality was higher for the TACI (total anterior circulation infarct) group compared to the other categories (p &lt; 0.0001). Hazard ratios for 5-year mortality in the final model were: 5.4 for age \u226565 years (p &lt; 0.0001), 2.8 for TACI (p &lt; 0.0001), 2.7 for previous vascular disease (p &lt; 0.01) and 1.9 for cardio-embolic risk according to the TOAST risk stratification (p &lt; 0.05). &lt;i&gt;Conclusions:&lt;\/i&gt; Our study extends the prognostic value of the OCSP classification to 5-year survival.<\/jats:p>","DOI":"10.1159\/000172631","type":"journal-article","created":{"date-parts":[[2008,11,14]],"date-time":"2008-11-14T12:50:46Z","timestamp":1226667046000},"page":"29-36","source":"Crossref","is-referenced-by-count":13,"title":["Five-Year Survival after First-Ever Ischaemic Stroke Is Worse in Total Anterior Circulation Infarcts: The SINPAC Cohort"],"prefix":"10.1159","volume":"27","author":[{"given":"M.","family":"Reggiani","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2008,11,15]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1161%2Fhs0901.094253"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016%2FS0895-4356%2802%2900572-3"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1161%2FSTROKEAHA.106.481465"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1159%2F000069936"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1007%2Fs10072-005-0463-0"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016%2F0140-6736%2891%2993206-O"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1136%2Fbmj.291.6510.1675"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1159%2F000008036"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1161%2F01.STR.0000185721.73445.fd"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1159%2F000092333"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1161%2F01.STR.27.11.1937"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1053%2Fjscd.2003.7"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1161%2F01.STR.0000013663.27776.DB"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1161%2F01.STR.0000017222.48968.6E"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016%2FS1474-4422%2803%2900352-1"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1093%2Fbrain%2Fawh636"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1161%2Fhs1101.098524"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1161%2F01.STR.24.6.796"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1161%2F01.STR.0000190118.02275.33"}],"container-title":["Cerebrovascular Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/172631","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/172631","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T00:24:27Z","timestamp":1745454267000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000172631"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,11,15]]},"references-count":19,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2009,1,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000172631","archive":["Portico"],"relation":{},"ISSN":["1015-9770","1421-9786"],"issn-type":[{"value":"1015-9770","type":"print"},{"value":"1421-9786","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,11,15]]}}}