{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T04:51:45Z","timestamp":1745470305410,"version":"3.40.4"},"reference-count":0,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[1982,1,1]],"date-time":"1982-01-01T00:00:00Z","timestamp":378691200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[1982,1,1]],"date-time":"1982-01-01T00:00:00Z","timestamp":378691200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Kidney Blood Press Res"],"published-print":{"date-parts":[[1982]]},"abstract":"<jats:p>Total CO&lt;sub&gt;2&lt;\/sub&gt; (CO&lt;sub&gt;2&lt;\/sub&gt;+HCO&lt;sup&gt;-&lt;\/sup&gt;&lt;sub&gt;3&lt;\/sub&gt;) was measured in alkaline extracts of quickly frozen rat renal cortex. The mean concentration calculated for tissue water was 18.7 \u00b1 SD 1.6 mEq\/1 (n=10) when that measured in plasma water was 23.5 \u00b1 1.7. In other experiments (n=6\u201310), the mean concentration in tissue water increased to 28.3 mEq\/1 after the animals were treated with benzolamide to inhibit carbonic anhydrase and to 38.1 mEq\/1 after they were infused with NaHCO&lt;sub&gt;3&lt;\/sub&gt;. On the other hand, the tissue concentration decreased to 14\u201315 mEq\/1 when they were hyperventilated or infused with HC1. Calculations based on published micropuncture data indicate that the usual intracellular concentration is 20\u201325 mEq\/1 or about twice that usually reported for skeletal muscle; and in contrast to muscle, the findings are suggestive of large variations in metabolic disorders.<\/jats:p>","DOI":"10.1159\/000172852","type":"journal-article","created":{"date-parts":[[2008,11,7]],"date-time":"2008-11-07T10:16:19Z","timestamp":1226052979000},"page":"157-164","source":"Crossref","is-referenced-by-count":0,"title":["Bicarbonate Concentrations in the Renal Cortex"],"prefix":"10.1159","volume":"5","author":[{"given":"James L.","family":"Gamble, Jr.","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne M.","family":"Skoff","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2008,11,6]]},"container-title":["Kidney and Blood Pressure Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/172852","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/172852","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T00:27:11Z","timestamp":1745454431000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000172852"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1982]]},"references-count":0,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2004,7,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000172852","archive":["Portico"],"relation":{},"ISSN":["1420-4096","1423-0143"],"issn-type":[{"type":"print","value":"1420-4096"},{"type":"electronic","value":"1423-0143"}],"subject":[],"published":{"date-parts":[[1982]]}}}