{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T04:51:48Z","timestamp":1745470308351,"version":"3.40.4"},"reference-count":0,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[1984,1,1]],"date-time":"1984-01-01T00:00:00Z","timestamp":441763200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[1984,1,1]],"date-time":"1984-01-01T00:00:00Z","timestamp":441763200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Kidney Blood Press Res"],"published-print":{"date-parts":[[1984]]},"abstract":"<jats:p>The simplification of the foot processes of the glomerular epithelial cells is the structural hallmark of proteinuria in nephrotic man and animals. The increased shear force in a filtrate funnelled within the lamina densa to simplified slit pores may decrease the friction of macromolecules which are prolate ellipsoids (cigar-shaped). The permeability of rigid long narrow proteins such as albumin, transferrin and immunoglobulin G may selectively increase when the slit pore is converted from a wide serpentine to a straight narrow space.<\/jats:p>","DOI":"10.1159\/000172932","type":"journal-article","created":{"date-parts":[[2008,11,7]],"date-time":"2008-11-07T10:16:19Z","timestamp":1226052979000},"page":"129-145","source":"Crossref","is-referenced-by-count":0,"title":["Permselectivity: Relation between Foot Process Simplification and Macromolecular Configuration"],"prefix":"10.1159","volume":"7","author":[{"given":"Robert L.","family":"Luke, III","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2008,11,7]]},"container-title":["Kidney and Blood Pressure Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/172932","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/172932","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T00:27:41Z","timestamp":1745454461000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000172932"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1984]]},"references-count":0,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2004,7,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000172932","archive":["Portico"],"relation":{},"ISSN":["1420-4096","1423-0143"],"issn-type":[{"type":"print","value":"1420-4096"},{"type":"electronic","value":"1423-0143"}],"subject":[],"published":{"date-parts":[[1984]]}}}