{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T01:00:25Z","timestamp":1777770025850,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2008,11,7]],"date-time":"2008-11-07T00:00:00Z","timestamp":1226016000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2008,11,7]],"date-time":"2008-11-07T00:00:00Z","timestamp":1226016000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiology"],"abstract":"<jats:p>Electrophysiological effects of lidocaine were studied in 27 patients with acute myocardial infarction complicated by bifascicular block (group I: 20), and complete A-V block (group II: 7). Lidocaine was administered intravenously in bolus doses of 100 mg each at intervals of 10 min. In group I, there was no significant change in the heart rate (Before (B) = 84.85 \u00b1 24.19, After (A) = 87.25 \u00b1 20.26 beats\/min) intra-atrial (PA) conduction time (B = 25 \u00b1 6.18, A = 27.22 \u00b1 6.69 ms), A-V nodal (AH) conduction (B = 111.5 \u00b1 56.12, A= 111.5 \u00b1 56.5 ms) or His bundle to ventricular (HV) activation time (B = 59.5 \u00b1 19.32, A = 61.25 \u00b1 18.62 ms) after lidocaine administration. In group II, 2 patients reverted to sinus rhythm, one with 1:1 conduction and the other with type II Wenckebach\u2019s block, while being prepared for the study, but both had complete A-V block within 1 h of the His bundle electrogram recordings. Of the remaining 5 patients, 4 had supra and 1 infra His A-V block. After lidocaine, 2 patients developed asystole. In the remaining 4 patients, there was no change in the escape rate or various conduction intervals.<\/jats:p>","DOI":"10.1159\/000173616","type":"journal-article","created":{"date-parts":[[2008,11,10]],"date-time":"2008-11-10T05:48:13Z","timestamp":1226296093000},"page":"333-340","source":"Crossref","is-referenced-by-count":4,"title":["Electrophysiological Effects of Lidocaine in Acute Myocardial Infarction with Bifascicular Block or Complete A-V Block"],"prefix":"10.1159","author":[{"given":"Nils","family":"Edvardsson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stig","family":"Holmberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kewal K.","family":"Talwar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bertil","family":"Olsson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2008,11,7]]},"container-title":["Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000173616","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T16:27:32Z","timestamp":1777480052000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000173616"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,11,7]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000173616","archive":["Portico"],"relation":{},"ISSN":["0008-6312","1421-9751"],"issn-type":[{"value":"0008-6312","type":"print"},{"value":"1421-9751","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,11,7]]}}}