{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T01:02:29Z","timestamp":1777770149780,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2008,11,11]],"date-time":"2008-11-11T00:00:00Z","timestamp":1226361600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2008,11,11]],"date-time":"2008-11-11T00:00:00Z","timestamp":1226361600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiology"],"abstract":"<jats:p>Left ventricular (LV) function was studied from end-systolic stress-shortening relations in 13 patients with mitral valve prolapse (MVP). Studies were made noninvasively using M-mode echocardiography with blood pressure measurements on the right arm from a Baumanometer cuff. Fifteen age and sex-matched normal subjects formed the control group. LV end-diastolic dimension was normal in MVP, while shortening fraction (p &lt; 0.05) and velocity of circumferential fiber shortening (mean Vcf) in the short axis of the ventricle were increased (p &lt; 0.05). Ventricular afterload, as measured by meridional end-systolic stress was reduced in MVP (p &lt; 0.01) but the slope of the stress-shortening curve was not different form normal. The decrease in end-systolic stress was related to the severity of prolapse (r = 0.63, p &lt; 0.05). The study implied that mid- or basal LV contractility was normal in MVP. The increased shortening fraction of the LV minor axis was in keeping with geometrical changes and a reduced ventricular afterload.<\/jats:p>","DOI":"10.1159\/000174198","type":"journal-article","created":{"date-parts":[[2008,11,12]],"date-time":"2008-11-12T08:17:04Z","timestamp":1226477824000},"page":"205-211","source":"Crossref","is-referenced-by-count":0,"title":["Left Ventricular Function from End-Systolic Stress-Shortening Relations in Mitral Valve Prolapse"],"prefix":"10.1159","author":[{"given":"Basil S.","family":"Lewis","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noga","family":"Lewis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arie","family":"Shefer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mervyn S.","family":"Gotsman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2008,11,11]]},"container-title":["Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000174198","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T16:29:24Z","timestamp":1777480164000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000174198"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,11,11]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000174198","archive":["Portico"],"relation":{},"ISSN":["0008-6312","1421-9751"],"issn-type":[{"value":"0008-6312","type":"print"},{"value":"1421-9751","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,11,11]]}}}