{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T16:34:08Z","timestamp":1759941248450,"version":"3.40.4"},"reference-count":0,"publisher":"S. Karger AG","issue":"2","license":[{"start":{"date-parts":[[1971,1,1]],"date-time":"1971-01-01T00:00:00Z","timestamp":31536000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[1971,1,1]],"date-time":"1971-01-01T00:00:00Z","timestamp":31536000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ann Nutr Metab"],"published-print":{"date-parts":[[1971]]},"abstract":"<jats:p>Severe malnutrition is described in a previously healthy 39-year-old man. He showed a marked loss of weight, with signs of peripheral oedema and muscular atrophy. A reduction was found of several protein fractions in blood, including haemoglobin, TIBC (total iron binding capacity), haptoglobin, albumin and lipoproteins. Amino acid metabolism was abnormal as indicated by low levels of the essential amino acids and high concentrations of some nonessential. The splanchnic uptake and peripheral muscle release of most amino acids were markedly attenuated. Folic acid in serum was slightly low. There was alkalosis, hypokalemia and an alkaline urine. No evidence was found of pancreatic insufficiency, nontropical sprue or protein-losing gastroenteropathy. Nitrogen balance studies, in combination with other findings suggested intermittent vomiting but this could not be observed by the ward personnel or the patient\u2019s family. However, when this diagnosis was presented to the patient and psychotherapy started, his clinical condition rapidly improved and most of the somatic manifestations gradually disappeared.<\/jats:p>","DOI":"10.1159\/000175325","type":"journal-article","created":{"date-parts":[[2008,11,14]],"date-time":"2008-11-14T12:50:46Z","timestamp":1226667046000},"page":"100-113","source":"Crossref","is-referenced-by-count":4,"title":["Severe Malnutrition in a Middle-Aged Man with Anorexia Nervosa"],"prefix":"10.1159","volume":"13","author":[{"given":"G.","family":"Carlberger","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Einarsson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Felig","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Hellstr\u00f6m","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Wahren","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Wengle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Zetterstr\u00f6m","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2008,11,13]]},"container-title":["Annals of Nutrition and Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/175325","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/175325","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T00:13:58Z","timestamp":1745453638000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000175325"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1971]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2004,7,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000175325","archive":["Portico"],"relation":{},"ISSN":["0250-6807","1421-9697"],"issn-type":[{"type":"print","value":"0250-6807"},{"type":"electronic","value":"1421-9697"}],"subject":[],"published":{"date-parts":[[1971]]}}}