{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T12:13:34Z","timestamp":1777896814725,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2008,11,21]],"date-time":"2008-11-21T00:00:00Z","timestamp":1227225600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2008,11,21]],"date-time":"2008-11-21T00:00:00Z","timestamp":1227225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Horm Res"],"abstract":"<jats:p>A review is presented of the current state of knowledge of responses of the hypothalamic-pituitary-thyroid axis and peripheral thyroxine metabolism to infectious disease. The effects of various infections and\/or toxins on thyroid hormone economy has been critically examined during multiple experimental and clinical conditions in a variety of animals, including man. Despite conflicting reports and some areas of controversy, the data does permit a synthesis of the major pathophysiology of thyroid events during infection.<\/jats:p>","DOI":"10.1159\/000178623","type":"journal-article","created":{"date-parts":[[2008,11,24]],"date-time":"2008-11-24T03:37:55Z","timestamp":1227497875000},"page":"112-128","source":"Crossref","is-referenced-by-count":15,"title":["The Response of the Thyroid Gland and Thyroid Hormone Metabolism to Infectious Disease"],"prefix":"10.1159","author":[{"given":"Leonard","family":"Wartofsky","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2008,11,21]]},"container-title":["Hormone Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000178623","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T08:38:15Z","timestamp":1777624695000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000178623"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,11,21]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000178623","archive":["Portico"],"relation":{},"ISSN":["0301-0163","1423-0046"],"issn-type":[{"value":"0301-0163","type":"print"},{"value":"1423-0046","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,11,21]]}}}