{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T14:58:04Z","timestamp":1790089084334,"version":"4.0.1"},"reference-count":37,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2008,1,1]],"date-time":"2008-01-01T00:00:00Z","timestamp":1199145600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2008,1,1]],"date-time":"2008-01-01T00:00:00Z","timestamp":1199145600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Fetal Diagn Ther"],"published-print":{"date-parts":[[2008]]},"abstract":"<jats:p>&lt;i&gt;Objective:&lt;\/i&gt; To evaluate the power of prenatal 2-D ultrasound examination in the 2nd trimester as a method of choice for accurate diagnosis of annular pancreas. &lt;i&gt;Methods:&lt;\/i&gt; Co-incidence of the double bubble sign (often accompanying gastroduodenal dilatation) together with a hyperechogenic band around the duodenum (corresponding with the tissue of annular pancreas) was used as a diagnostic criterion. Findings from postnatal surgery served for verification. &lt;i&gt;Results:&lt;\/i&gt; From 7,897 screened pregnancies, annular pancreas was proven in the cases where both signs were present, but never without the hyperechogenic band (N&lt;sub&gt;1&lt;\/sub&gt; = 3, N&lt;sub&gt;2&lt;\/sub&gt; = 3, p \u2264 0.05). Sensitivity and specificity were 100%. &lt;i&gt;Conclusions:&lt;\/i&gt; More multicentric studies are required to test this approach. The following diagnostic strategy is reasonable at the present time: when the double bubble sign is discovered, always suspect annular pancreas and look for the second sign: hyperechogenic bands around the duodenum. Also look for known associated anomalies, and vice versa, if any of associated anomalies are noted, also search specifically for the signs of annular pancreas.<\/jats:p>","DOI":"10.1159\/000178759","type":"journal-article","created":{"date-parts":[[2008,11,29]],"date-time":"2008-11-29T14:20:02Z","timestamp":1227968402000},"page":"483-490","source":"Crossref","is-referenced-by-count":32,"title":["Prenatal Diagnosis of Annular Pancreas: Reliability of the Double Bubble Sign with Periduodenal Hyperechogenic Band"],"prefix":"10.1159","volume":"24","author":[{"given":"Robert","family":"Dankovcik","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan 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