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Karger AG","issue":"1","license":[{"start":{"date-parts":[[2008,12,15]],"date-time":"2008-12-15T00:00:00Z","timestamp":1229299200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2008,12,15]],"date-time":"2008-12-15T00:00:00Z","timestamp":1229299200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuroimmunomodulation"],"published-print":{"date-parts":[[2009]]},"abstract":"<jats:p>Most reports of autoimmune response during infection with the parasite &lt;i&gt;Trypanosoma cruzi&lt;\/i&gt; have dealt with the cardiomyopathic form of Chagas\u2019 disease, but little is known about the mechanisms of tissue damage involved in the gastrointestinal form, which was studied here. Chronically infected patients with a severe gastrointestinal form of Chagas\u2019 disease present increased antibody production and proliferative responses to peripheral myelin components, such as myelin basic protein (MBP), which is homologous to the P1 protein fraction of peripheral myelin. T lymphocytes preferentially recognize a region on the MBP molecule (1\u201330), which suggests that the MBP is a potential target on the peripheral nerve for autoimmune reactions in patients with gastrointestinal lesions resulting from Chagas\u2019 disease.<\/jats:p>","DOI":"10.1159\/000179667","type":"journal-article","created":{"date-parts":[[2008,12,12]],"date-time":"2008-12-12T15:27:44Z","timestamp":1229095664000},"page":"54-62","source":"Crossref","is-referenced-by-count":14,"title":["Neuropathy of Gastrointestinal Chagas\u2019 Disease: Immune Response to Myelin Antigens"],"prefix":"10.1159","volume":"16","author":[{"given":"Elaine C.","family":"Oliveira","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00e1rcia M.","family":"Fujisawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dannie E.M.","family":"Hallal Longo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandro S.","family":"Farias","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juliana","family":"Contin Moraes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Elena","family":"Guariento","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eros Ant\u00f4nio","family":"de Almeida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mario Jos\u00e9 A.","family":"Saad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Langone","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcos H.","family":"Toyama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nelson A.","family":"Andreollo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leonilda M.B.","family":"Santos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2008,12,15]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1159%2F000058703"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016%2FS0001-706X%2801%2900202-9"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.2741%2F1023"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.pt.2005.08.013"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1073%2Fpnas.92.8.3541"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1172%2FJCI118969"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1084%2Fjem.175.1.29"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1159%2F000200488"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1038%2F296034a0"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1002%2Fana.410180609"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1006%2Fexpr.1998.4279"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1080%2F00327487208061467"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1471-4159.1973.tb07519.x"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1002%2Fana.410090710"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1590%2FS0074-02761990000400028"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.jaut.2005.01.006"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1084%2Fjem.169.3.641"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1073%2Fpnas.88.14.5993"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016%2FS0169-4758%2897%2901073-9"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1002%2Feji.1830170720"}],"container-title":["Neuroimmunomodulation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/179667","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/179667","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T00:12:27Z","timestamp":1745453547000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000179667"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,12,15]]},"references-count":20,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2009,1,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000179667","archive":["Portico"],"relation":{},"ISSN":["1021-7401","1423-0216"],"issn-type":[{"value":"1021-7401","type":"print"},{"value":"1423-0216","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,12,15]]}}}