{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T16:05:50Z","timestamp":1777910750656,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2008,11,27]],"date-time":"2008-11-27T00:00:00Z","timestamp":1227744000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2008,11,27]],"date-time":"2008-11-27T00:00:00Z","timestamp":1227744000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nephron"],"abstract":"<jats:p>Studies of a 60-year-old woman with renal tubular acidosis, a Fanconi syndrome and nonmyelomatous hypergammaglobulinemia are described. They demonstrate bicarbonate wasting in association with a normal capacity for acidification of the urine when serum bicarbonate was educed by ammonium chloride loading. The presence of a 1:2,500 latex titer, hypergammaglobulinemia, positive Schirmer\u2019s test, leukopenia and interstitial nephritis suggest that the patient has a disorder closely related to Sj\u00f6gren\u2019s syndrome. Over a 3-year follow-up period progressive improvement in renal function has occurred despite the persistence of an elevated serum IgG, high latex titer and leukopenia.<\/jats:p>","DOI":"10.1159\/000180152","type":"journal-article","created":{"date-parts":[[2008,11,29]],"date-time":"2008-11-29T09:20:02Z","timestamp":1227950402000},"page":"208-219","source":"Crossref","is-referenced-by-count":15,"title":["Proximal Renal Tubular Acidosis and the Fanconi Syndrome in a Patient with Hypergammaglobulinemia"],"prefix":"10.1159","author":[{"given":"D.E.","family":"Kamm","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.S.","family":"Fischer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2008,11,27]]},"container-title":["Nephron"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/180152","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000180152","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T15:05:27Z","timestamp":1777647927000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000180152"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,11,27]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000180152","archive":["Portico"],"relation":{},"ISSN":["1660-8151","2235-3186"],"issn-type":[{"value":"1660-8151","type":"print"},{"value":"2235-3186","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,11,27]]}}}