{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T16:21:29Z","timestamp":1777911689917,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2008,12,3]],"date-time":"2008-12-03T00:00:00Z","timestamp":1228262400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2008,12,3]],"date-time":"2008-12-03T00:00:00Z","timestamp":1228262400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nephron"],"abstract":"<jats:p>Hand bone calcium content [Ca] has been measured by local neutron analysis in hemodialyzed patients free of signs of osteomalacia before and 6\u201312 months after treatment with vitamin D metabolites, and it has been compared to some iliac bone histomorphometric parameters. With 1,25-(OH)&lt;sub&gt;2&lt;\/sub&gt;D3 alone, [Ca] increases significantly at the 6th month of treatment (p &lt; 0.001) but not from the 6th to the 12th month. With 1\u03b1-(OH)D3 + 25-(OH)D3 the same phenomenon is observed at the 6th and 12th months of treatment. Before treatment, [Ca] was correlated negatively with the osteoid surfaces (OS) (r = \u2013 0.62, p = 0.01) and the number of osteoclasts per square millimeter (Ocl\/mm2)(r = -0.79, p &lt; 0.001). At the 6th month of treatment, [Ca] was still correlated negatively with OS (r = \u2013 0.42, p = 0.05) and with Ocl\/mm2 (r = -0.60, p &lt; 0.005). At the 12th month, the two negative correlations decreased but remained significant (r = -0.42, p = 0.05; r = -0.45, p = 0.05). These data suggest that (1) hand bone calcium analysis by neutron activation permits to follow up the peripheral bone mineral content in hemodialyzed patients and (2) the [Ca] increase only observed during the first months of treatment with vitamin D metabolites probably result from an attenuation of secondary hyperparathyroidism.<\/jats:p>","DOI":"10.1159\/000183021","type":"journal-article","created":{"date-parts":[[2008,12,8]],"date-time":"2008-12-08T08:19:42Z","timestamp":1228724382000},"page":"228-233","source":"Crossref","is-referenced-by-count":3,"title":["Advantage of Hand Bone Calcium Content Measurement by Local Neutron Activation Analysis for Following Up Hemodialysis Patients"],"prefix":"10.1159","author":[{"given":"D.","family":"Kuntz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Maziere","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.L.","family":"Sebert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Moriniere","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.J.","family":"Meuniere","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Duquesnoy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Fournier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2008,12,3]]},"container-title":["Nephron"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/183021","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000183021","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T15:32:38Z","timestamp":1777649558000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000183021"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,12,3]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000183021","archive":["Portico"],"relation":{},"ISSN":["1660-8151","2235-3186"],"issn-type":[{"value":"1660-8151","type":"print"},{"value":"2235-3186","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,12,3]]}}}