{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T17:43:34Z","timestamp":1777916614498,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2008,12,9]],"date-time":"2008-12-09T00:00:00Z","timestamp":1228780800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2008,12,9]],"date-time":"2008-12-09T00:00:00Z","timestamp":1228780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nephron"],"abstract":"<jats:p>The concentrations of organochlorine pesticides in serum have been determined by GC and electron capture detection. Studies were performed in 7 nondialyzed, 10 dialyzed and 6 healthy persons. Only hexachlorobenzene (HCB) and 1, 1-di(4-chlorophenyl)-2,2-dichloroethene (pp\u2019-DDE) were consistently present. No interference by other pesticides or polychlorinated biphenyls was found by checking with GC-MS. For the nondialyzed uremic patients the average HCB concentration was 16.2 nmol\/l (\u03c3 = 6.7, n = 7), and the pp\u2019-DDE level 26.4 nmol\/l (\u03c3 = 31.4, n = 7). For the dialyzed uremic patients the average HCB level was 15.5 nmol\/l (\u03c3 = 11.2, n = 10) before dialysis and 17.2 nmol\/l (\u03c3 = 14.4, n = 8) after dialysis, the concentration of pp\u2019-DDE was 27.0 nmol\/l (\u03c3 = 38.4, n = 10) before dialysis and 28.0 nmol\/l (\u03c3 = 37.4, n = 8) after dialysis. For the healthy persons the average concentration of HCB was 7.7 nmol\/l (\u03c3 = 1.8, n = 6) and the concentration of pp\u2019-DDE was 20.1 nmol\/l (\u03c3 = 10.4, n = 6). HCB concentrations were significantly higher in serum of dialyzed and nondialyzed uremic patients than in controls (Wilcoxon\u2019s test).<\/jats:p>","DOI":"10.1159\/000184915","type":"journal-article","created":{"date-parts":[[2008,12,15]],"date-time":"2008-12-15T06:03:14Z","timestamp":1229320994000},"page":"217-221","source":"Crossref","is-referenced-by-count":12,"title":["Hexachlorobenzene and 1, 1-di(4-Chlorophenyl)-2,2-Dichloroethene in Serum of Uremic Patients and Healthy Persons: Determination by Capillary Gas Chromatography and Electron Capture Detection"],"prefix":"10.1159","author":[{"given":"Gerard A.","family":"Rutten","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.C.","family":"Schoots","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raymond","family":"Vanholder","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rita","family":"DeSmet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Severin M.","family":"Ringoir","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carel A.","family":"Cramers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2008,12,9]]},"container-title":["Nephron"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/184915","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000184915","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T17:52:38Z","timestamp":1777657958000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000184915"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,12,9]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000184915","archive":["Portico"],"relation":{},"ISSN":["1660-8151","2235-3186"],"issn-type":[{"value":"1660-8151","type":"print"},{"value":"2235-3186","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,12,9]]}}}