{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T16:37:33Z","timestamp":1785343053452,"version":"3.55.0"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2008,12,9]],"date-time":"2008-12-09T00:00:00Z","timestamp":1228780800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2008,12,9]],"date-time":"2008-12-09T00:00:00Z","timestamp":1228780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nephron"],"abstract":"<jats:p>To assess the reasons for the frequent cardiovascular complications in patients with end-stage renal disease (ESRD), 61 out of 131 normotensive ESRD patients originally examined (mean ESRD duration: 71 \u00b1 41 months) were followed over 2.5 years by echo-, electro- and mechanocardiography. Clinical and biochemical parameters were comparable. The prevalence of pericardial effusion (3%), pericardial thickening (14%), aortic valve sclerosis (14%) and mitral valve anulus sclerosis (12%) was unchanged. The interventricular septum diameter (14.3 \u00b1 3.0 vs. 16.4 \u00b1 3.4 mm), index of left-ventricular (LV) wall asymmetry (1.25 \u00b1 0.30 vs. 1.52 \u00b1 0.36) and left atrial diameter (38.3 \u00b1 5.4 vs. 42.6 \u00b1 3 mm) increased (p &lt; 0.001). The LV end-systolic diameter decreased slightly (35.8 + 6.3 vs. 34.2 \u00b1 6.4 mm; p &lt; 0.05), with no significant changes for end-diastolic diameter (50.4 \u00b1 6.3 vs. 49.3 \u00b1 6.1 mm), muscle mass index (189 \u00b1 57 vs. 197 \u00b1 50 g\/m2), stroke volume (86.1 \u00b1 26.2 vs. 85.7 \u00b1 26.7 7 ml\/m2) and fractional shortening (29.1 \u00b1 7 vs. 30.8 \u00b1 8.6%). We conclude that the predominant finding in ESRD is an LV hypertrophy progressing towards an asymmetric septum hypertrophy, while the increase of the primarily enlarged left atrial diameter over 30 months reflects a further deterioration of the diastolic LV dysfunction.<\/jats:p>","DOI":"10.1159\/000185077","type":"journal-article","created":{"date-parts":[[2008,12,18]],"date-time":"2008-12-18T13:06:57Z","timestamp":1229605617000},"page":"284-290","source":"Crossref","is-referenced-by-count":74,"title":["Analysis of Left-Ventricular Changes Associated with Chronic Hemodialysis"],"prefix":"10.1159","author":[{"given":"J\u00fcrgen","family":"H\u00fcting","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wilfried","family":"Kramer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georg","family":"Sch\u00fctterle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Volker","family":"Wizemann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2008,12,9]]},"container-title":["Nephron"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/185077","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000185077","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T17:53:38Z","timestamp":1777658018000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000185077"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,12,9]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000185077","archive":["Portico"],"relation":{},"ISSN":["1660-8151","2235-3186"],"issn-type":[{"value":"1660-8151","type":"print"},{"value":"2235-3186","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,12,9]]}}}