{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T09:12:00Z","timestamp":1759482720851,"version":"3.40.4"},"reference-count":21,"publisher":"S. Karger AG","issue":"2","license":[{"start":{"date-parts":[[2009,1,16]],"date-time":"2009-01-16T00:00:00Z","timestamp":1232064000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2009,1,16]],"date-time":"2009-01-16T00:00:00Z","timestamp":1232064000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nephron Clin Pract"],"abstract":"<jats:p>&lt;i&gt;Background:&lt;\/i&gt; Anemia is a common complication of chronic kidney disease (CKD), but anemia treatment may be less comprehensive than guidelines suggest. &lt;i&gt;Methods:&lt;\/i&gt; The study population (n = 11,754) included general Medicare recipients with Parts A and B coverage before January 1, 2001, aged \u226565 years on January 1, 2001, and alive with Medicare as primary payer through December 31, 2001. Time-dependent proportional hazards models were used to investigate predictors of erythropoiesis-stimulating agent (ESA) use, adjusted for comorbid conditions and severity-of-disease variables as time-dependent, and age, sex, and race as fixed variables. ESA use was defined during 2002 and time-dependent variables during 2001\u20132002. &lt;i&gt;Results:&lt;\/i&gt; Only 839 patients (7%) received ESAs. Characteristics significantly predictive of ESA use (p &lt; 0.05) were: outpatient specialty services, nephrology and hematology\/oncology\/medical oncology (RR 6.92); outpatient specialty services, hematology\/oncology\/medical oncology (RR 6.02); outpatient specialty services, nephrology (RR 3.44); inpatient principle procedure, other operations on vessels (RR 1.68); transfusions (RR 1.54), hypertension (RR 1.50); congestive heart failure (RR 1.34); home oxygen (RR 1.28). &lt;i&gt;Conclusions:&lt;\/i&gt; Access to anemia treatment may be an important marker for access to CKD care. Clinical trials are needed to assess effects of early referral and more comprehensive anemia treatment.<\/jats:p>","DOI":"10.1159\/000191207","type":"journal-article","created":{"date-parts":[[2009,1,20]],"date-time":"2009-01-20T08:53:22Z","timestamp":1232441602000},"page":"c141-c148","source":"Crossref","is-referenced-by-count":5,"title":["Predictors of ESA Use in the Non-Dialysis Chronic Kidney Disease Population with Anemia"],"prefix":"10.1159","volume":"111","author":[{"given":"Allan J.","family":"Collins","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haifeng","family":"Guo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David T.","family":"Gilbertson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian D.","family":"Bradbury","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2009,1,16]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1053%2Fajkd.2002.32799"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1056%2FNEJMoa041031"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1056%2FNEJMoa011161"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1056%2FNEJMoa011303"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1056%2FNEJMoa065485"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1177%2F106286069901400607"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1053%2Fj.ajkd.2005.04.029"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.2165%2F00115677-200210080-00007"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1185%2F030079904X2763"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.amjhyper.2004.03.385"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1097%2F01.ASN.0000034200.82278.DC"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1053%2Fajkd.2001.27699"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1053%2Fajkd.1998.v31.pm9506677"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1097%2F01.ASN.0000046047.66958.C3"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1053%2Fajkd.2001.21305"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1159%2F000047713"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.jclinepi.2004.05.002"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1053%2Fj.ajkd.2007.09.015"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1002%2F%28SICI%291099-1557%28200001%2F02%299%3A1%3C37%3A%3AAID-PDS471%3E3.0.CO%3B2-U"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.7326%2F0003-4819-139-2-200307150-00013"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1475-6773.2005.00482.x"}],"container-title":["Nephron Clinical Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/191207","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/191207","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T23:18:55Z","timestamp":1745450335000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000191207"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,1,16]]},"references-count":21,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2009,2,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000191207","archive":["Portico"],"relation":{},"ISSN":["1660-2110"],"issn-type":[{"type":"electronic","value":"1660-2110"}],"subject":[],"published":{"date-parts":[[2009,1,16]]}}}